I-Paxlovid Boceprevir Intermediate CAS 565456-77-1 Assay ≥99.0%

Incazelo emfushane:

Igama: (1R,2S,5S)-6,6-Dimethyl-3-azabicyclo[3.1.0]hexane-2-Carboxylic Acid Methyl Ester Hydrochloride

I-CAS: 565456-77-1

Ukubukeka: Impushana Emhlophe ukuya Emhlophe

Isivivinyo: ≥99.0%

Okumaphakathi kwe-PF-07321332 Paxlovid (CAS 2628280-40-8) kanye ne-Boceprevir (CAS 394730-60-0)

Ikhwalithi Ephezulu, Ukukhiqizwa Kwezohwebo

Inquiry: alvin@ruifuchem.com

Thumela i-imeyili kithi

Imininingwane Yomkhiqizo

Imikhiqizo Ehlobene

Omaka bomkhiqizo

Incazelo:

I-Commercial Supply PF-07321332 I-Paxlovid Izixhumanisi Ezihlobene Nekhwalithi Ephezulu
I-L-tert-Leucine (H-Tle-OH) CAS 20859-02-3
I-Caronic Anhydride CAS 67911-21-1
(1R,2S,5S)-6,6-Dimethyl-3-azabicyclo[3.1.0]hexane-2-Carboxylic Acid Methyl Ester Hydrochloride 565456-77-1
I-Methyl (S)-2-(Boc-amino)-3-[(S)-2-oxo-3-pyrrolidinyl]propanoate CAS 328086-60-8
6,6-Dimethyl-3-azabicyclo[3.1.0]hexane CAS 943516-54-9

Chemical Properties:

Igama Lekhemikhali	(1R,2S,5S)-6,6-Dimethyl-3-azabicyclo[3.1.0]hexane-2-Carboxylic Acid Methyl Ester Hydrochloride
Omqondofana	I-Methyl (1R,2S,5S)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylate Hydrochloride
Inombolo ye-CAS	565456-77-1
Inombolo yeCAT	I-RF-PI318
Isimo Sesitoko	Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani
I-Molecular Formula	I-C9H15NO2.ClH
Isisindo samangqamuzana	205.683
Ibhrendi	I-Ruifu Chemical

Imininingwane:

Into	Imininingwane
Ukubukeka	Impushana Emhlophe Kuya Kumhlophe
Ukuhlonza A	I-IR: Ifana Nereferensi Into
Ukuhlonza B	Isikhathi Sokugcina: Sifana Nereferensi Into
I-Enantiomer	≤0.15%
Ukungcola Okuhlobene (nge-HPLC)
Ukungcola Okungaziwa	≤0.20%
Ukungcola Okuphelele	≤1.0%
Amanzi	≤0.50%
Izinsalela ekushiseni	≤0.10%
Izinsimbi Ezisindayo	≤20ppm
Isivivinyo	≥99.0%
Izinga Lokuhlola	I-Enterprise Standard
Ukusetshenziswa	Okumaphakathi kwe-PF-07321332 Paxlovid (CAS 2628280-40-8) kanye ne-Boceprevir (CAS 394730-60-0)

Iphakheji nesitoreji:

Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, isigubhu seCardboard, 25kg/Drum, noma ngokwezidingo zekhasimende.

Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni, umswakama kanye nezinambuzane.

Izinzuzo:

I-FAQ:

Isicelo:

(1R,2S,5S)-6,6-Dimethyl-3-azabicyclo[3.1.0]hexane-2-Carboxylic Acid Methyl Ester Hydrochloride (CAS 565456-77-1) iphuma ku-azabicyclohexane esetshenziswa ekulungiseleleni i-hepatitis C. virus (HCV) NS3 serine protease inhibitor.Kuphakathi kwe-PF-07321332 Paxlovid (CAS 2628280-40-8) kanye ne-Boceprevir (CAS 394730-60-0).I-PF-07321332 iyi-inhibitor enamandla futhi esebenza ngomlomo i-SARS-CoV 3C-like protease (3CLPRO) .I-PF-07321332 iqondise kugciwane le-SARS-CoV-2 futhi ingasetshenziselwa ukucwaninga kabusha kwe-COVID-19.I-Boceprevir (INN, igama lokuhweba i-Victrelis) iyi-protease inhibitor esetshenziswa njengokwelapha i-hepatitis C genotype 1. Ibophezela kusayithi elisebenzayo le-HCV nonstructural 3 NS3 (HCV).Yayithuthukiswa yi-Schering-Plough, kodwa manje ithuthukiswa yi-Merck kusukela i-Schering yatholwa ngo-2009. Yagunyazwa yi-FDA ngoMeyi 13, 2011.