I-Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate CAS 184177-81-9 Posaconazole Ikhwalithi Ephakathi Ephakeme
Ukunikezwa Kwefekthri Ngokuhlanzeka Okuphezulu kanye Nekhwalithi Ezinzile
Ukukhiqizwa Kwezohwebo Okuhlobene Ne-Posaconazole
I-Posaconazole CAS 171228-49-2
I-Posaconazole I-POA Ephakathi CAS 149809-43-8
I-Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate CAS 184177-81-9
1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine CAS 74853-08-0
2-[(1S,2S)-1-Ethyl-2-(phenylmethoxy)propyl]hydrazinecarboxal CAS 170985-85-0
I-Diethyl L-(+)-Tartrate CAS 87-91-2
Igama Lekhemikhali | I-Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate |
Omqondofana | I-Posaconazole Ephakathi |
Inombolo ye-CAS | 184177-81-9 |
Inombolo yeCAT | I-RF-PI290 |
Isimo Sesitoko | Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani |
I-Molecular Formula | I-C23H23N3O3 |
Isisindo samangqamuzana | 389.45 |
Ukuminyana | 1.296 |
Isimo Sokuthumela | Ngaphansi Kwezinga Lokushisa Le-Ambient |
Ibhrendi | I-Ruifu Chemical |
Into | Imininingwane |
Ukubukeka | I-Pale Brown kuya kuMpunga Ompunga |
Ukuhlanzeka / Indlela Yokuhlaziya | ≥99.0% (HPLC) |
Ukulahlekelwa Ekumisweni | ≤0.50% |
Izinsalela ekushiseni | ≤0.20% |
Izinsimbi Ezisindayo | ≤20ppm |
Ukungcola Okukodwa | ≤0.50% |
Ukungcola Okuphelele | ≤1.0% |
Izinga Lokuhlola | I-Enterprise Standard |
Ukusetshenziswa | I-Posaconazole emaphakathi (CAS 171228-49-2) |
Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, isigubhu seCardboard, 25kg/Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni, umswakama kanye nezinambuzane.
I-Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate (CAS 184177-81-9) iyi-Intermediate of Posaconazole (CAS 171228-49-2).I-Posaconazole iyi-spectrum ebanzi, isizukulwane sesibili, inhlanganisela ye-triazole enomsebenzi we-antifungal.Yagunyazwa ukusetshenziswa kwezokwelapha e-United States ngoSepthemba 2006, futhi iyatholakala njengemithi ejwayelekile.I-Posaconazole iyisidakamizwa se-triazole antifungal esimakethwa e-United States ngabakwa-Schering-Plough ngaphansi kwegama lokuhweba elithi Noxafil.I-Posaconazole isebenza ngokuphazamisa ukupakishwa okuseduze kwamaketanga e-acyl e-phospholipids, iphazamisa ukusebenza kwezinhlelo ezithile ze-enzyme eziboshwe ulwelwesi ezifana ne-ATPase nama-enzyme ohlelo lokuthutha ama-electron, ngaleyo ndlela kuvimbela ukukhula kwesikhunta.Lokhu ikwenza ngokuvimbela ukuhlanganiswa kwe-ergosterol ngokuvimbela i-enzyme i-lanosterol 14a-demethylase kanye nokuqoqwa kwama-methylated sterol precursors.