I-Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate CAS 184177-81-9 Posaconazole Ikhwalithi Ephakathi Ephakeme

Incazelo emfushane:

Igama Lekhemikhali: Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate

CAS: 184177-81-9

I-Intermediate ye-Posaconazole (CAS 171228-49-2) I-Triazole Antifungal Agent

Ikhwalithi Ephezulu, Ukukhiqizwa Kwezohwebo

Inquiry: alvin@ruifuchem.com


Imininingwane Yomkhiqizo

Imikhiqizo Ehlobene

Omaka bomkhiqizo

Incazelo:

Chemical Properties:

Igama Lekhemikhali I-Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate
Omqondofana I-Posaconazole Ephakathi
Inombolo ye-CAS 184177-81-9
Inombolo yeCAT I-RF-PI290
Isimo Sesitoko Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani
I-Molecular Formula I-C23H23N3O3
Isisindo samangqamuzana 389.45
Ukuminyana 1.296
Isimo Sokuthumela Ngaphansi Kwezinga Lokushisa Le-Ambient
Ibhrendi I-Ruifu Chemical

Imininingwane:

Into Imininingwane
Ukubukeka I-Pale Brown kuya kuMpunga Ompunga
Ukuhlanzeka / Indlela Yokuhlaziya ≥99.0% (HPLC)
Ukulahlekelwa Ekumisweni ≤0.50%
Izinsalela ekushiseni ≤0.20%
Izinsimbi Ezisindayo ≤20ppm
Ukungcola Okukodwa ≤0.50%
Ukungcola Okuphelele ≤1.0%
Izinga Lokuhlola I-Enterprise Standard
Ukusetshenziswa I-Posaconazole emaphakathi (CAS 171228-49-2)

Iphakheji nesitoreji:

Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, isigubhu seCardboard, 25kg/Drum, noma ngokwezidingo zekhasimende.

Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni, umswakama kanye nezinambuzane.

Izinzuzo:

1

I-FAQ:

Isicelo:

I-Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate (CAS 184177-81-9) iyi-Intermediate of Posaconazole (CAS 171228-49-2).I-Posaconazole iyi-spectrum ebanzi, isizukulwane sesibili, inhlanganisela ye-triazole enomsebenzi we-antifungal.Yagunyazwa ukusetshenziswa kwezokwelapha e-United States ngoSepthemba 2006, futhi iyatholakala njengemithi ejwayelekile.I-Posaconazole iyisidakamizwa se-triazole antifungal esimakethwa e-United States ngabakwa-Schering-Plough ngaphansi kwegama lokuhweba elithi Noxafil.I-Posaconazole isebenza ngokuphazamisa ukupakishwa okuseduze kwamaketanga e-acyl e-phospholipids, iphazamisa ukusebenza kwezinhlelo ezithile ze-enzyme eziboshwe ulwelwesi ezifana ne-ATPase nama-enzyme ohlelo lokuthutha ama-electron, ngaleyo ndlela kuvimbela ukukhula kwesikhunta.Lokhu ikwenza ngokuvimbela ukuhlanganiswa kwe-ergosterol ngokuvimbela i-enzyme i-lanosterol 14a-demethylase kanye nokuqoqwa kwama-methylated sterol precursors.

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