I-Pirfenidone CAS 53179-13-8 Ubumsulwa ≥99.0% IPF
Nikeza Ngokuhlanzeka Okuphezulu, Ukukhiqiza Kwezentengiso
Igama Lekhemikhali: I-Pirfenidone
CAS: 53179-13-8
| Igama Lekhemikhali | I-Pirfenidone |
| Omqondofana | I-Perfenidone;I-5-Methyl-1-Phenylpyridine-2 (1H) -enye;PFD;I-S-7701;I-AMR-69 |
| Inombolo ye-CAS | 53179-13-8 |
| Inombolo yeCAT | I-RF-API108 |
| Isimo Sesitoko | Kukhona kusitoki |
| I-Molecular Formula | I-C12H11NO |
| Isisindo samangqamuzana | 185.22 |
| I-Melting Point | 96.0 ukuze 97.0℃ |
| Ukuncibilika | I-Soluble ku-DMSO |
| Ibhrendi | I-Ruifu Chemical |
| Into | Imininingwane |
| Ukubukeka | I-Crystalline Powder Emhlophe Kuya Kuphuzi Ephuzi |
| Ukuhlonza | IR |
| Ubumsulwa | ≥99.0% |
| Ukulahlekelwa Ekumisweni | ≤0.50% |
| I-Sulfated Ash | ≤0.20% |
| Ukungcola Okukodwa | ≤0.50% |
| Ukungcola Okuphelele | ≤1.0% |
| Izinsimbi Ezisindayo | ≤20ppm |
| Izinga Lokuhlola | I-Enterprise Standard |
| Ukusetshenziswa | I-API, Idiopathic Pulmonary Fibrosis (IPF) |
Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni nakumswakama.
I-Pirfenidone (CAS: 53179-13-8) iseqenjini lemithi ebizwa ngokuthi ama-antifibrotic agents.I-Pirfenidone ibonise umsebenzi ezimeni eziningi ze-fibrotic, okuhlanganisa lezo zamaphaphu, izinso nesibindi.Kuthinta amasosha omzimba wakho futhi kunciphisa inani le-fibrosis (izibazi) emaphashini.I-Pirfenidone ngomunye wemithi emibili egunyazwe e-Canada ukwelapha i-Idiopathic Pulmonary Fibrosis (IPF).I-Pirfenidone iyi-inhibitor yokukhiqizwa kwe-TGF-β kanye nokukhiqizwa kwe-collagen evuselelwe i-TGF-β, inciphisa ukukhiqizwa kwe-TNF-α ne-IL-1β, futhi inezindawo zokulwa ne-fibrotic kanye ne-anti-inflammatory.Yaqala ukugunyazwa eJapane ukuze zelashwe iziguli ezine-idiopathic pulmonary fibrosis ngemva kokuhlolwa komtholampilo, ngaphansi kwegama lokuhweba le-Pirespa nguShionogi, ngo-2008. Yagunyazwa ukusetshenziswa e-European Union ngo-2011, eCanada ngo-2012, futhi e-United States ngo-Okthoba 2014.
