I-Posaconazole CAS 171228-49-2 API Factory Triazole Antifungal Agent High Quality
I-Factory Supply Related Intermediate, Ukukhiqizwa Kwezentengiso
I-Posaconazole CAS 171228-49-2
I-Posaconazole I-POA Ephakathi CAS 149809-43-8
I-Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate CAS 184177-81-9
1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine CAS 74853-08-0
2-[(1S,2S)-1-Ethyl-2-(phenylmethoxy)propyl]hydrazinecarboxal CAS 170985-85-0
I-Diethyl L-(+)-Tartrate CAS 87-91-2
Igama Lekhemikhali | I-Posaconazole |
Omqondofana | I-POS;I-SCH 56592;4-- [4-4- [[(3R,5R)-5-(2,4-Difluorophenyl)-5-(1,2,4-triazol-1-ylmethyl)oxolan-3-yl] methoxy]phenyl]piperazin-1-yl]phenyl]-2-[(2S,3S)-2-hydroxypentan-3-yl]-1,2,4-triazol-3-one |
Inombolo ye-CAS | 171228-49-2 |
Inombolo yeCAT | I-RF-API77 |
Isimo Sesitoko | Esitokweni, Isikali Sokukhiqiza Sifika Emakhulwini Amakhilogremu |
I-Molecular Formula | I-C37H42F2N8O4 |
Isisindo samangqamuzana | 700.78 |
Ukuminyana | 1.36 g/cm3 |
Ukuncibilika | I-Soluble ku-DMSO, Ayinyibiliki emanzini |
Isimo Sokuthumela | Kuthunyelwe Ngaphansi Kwezinga Lokushisa Le-Ambient |
Ibhrendi | I-Ruifu Chemical |
Into | Imininingwane |
Ukubukeka | I-Crystalline Powder emhlophe ukuya kokumhlophe |
Ukuhlonza A | IR: I-spectrum yokumuncwa kwe-infrared yomkhiqizo kufanele ihambisane naleyo yereferensi yento. |
Ukuhlonza B | Isikhathi sokugcina se-HPLC sifana nento eyisethenjwa |
I-Melting Point | 167.0 ~ 171.0℃ |
Ukuzungezisa Okuthile [a]20 | -24.0° ~ -28.0° (C=1, CHCL3) |
Amanzi (KF) | ≤1.0% |
Izinsalela ekushiseni | ≤0.10% |
Izinto Ezihlobene | |
HT 909-24 | ≤0.20% |
Noma yikuphi Ukungcola Komuntu Ngamunye | ≤0.10% |
Ukungcola Okuphelele | ≤1.0% |
Izincibilikisi Ezisele | |
I-Methanol | ≤3000ppm |
I-Methyl tert-Butyl Ether | ≤5000ppm |
Isopropanol | ≤5000ppm |
I-Dimethyl Sulfoxide | ≤5000ppm |
I-Dichloromethane | ≤600ppm |
Isivivinyo | 98.0%~102.0% (Ibalwe ngokomisiwe) |
Izinsimbi Ezisindayo | ≤10ppm |
Isomer | I-Enantiomer ≤0.10% |
Noma Ikuphi Ukungcola Komuntu Ngamunye ≤0.10% | |
Ukungcola Okuphelele ≤1.0% | |
Izinga Lokuhlola | Izinga lebhizinisi;USP;BP;I-EP Standard |
Ukusetshenziswa | I-API, Umenzeli we-Triazole Antifungal |
Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, isigubhu seCardboard, 25kg/Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni, umswakama kanye nezinambuzane.
I-Posaconazole (i-CAS 171228-49-2), iyinhlanganisela ebanzi, isizukulwane sesibili, i-triazole enomsebenzi we-antifungal, eyethulwe e-UK, iyilungu elisha lesigaba se-azole sama-antifungal agents ukufinyelela emakethe.Ikhonjiswe ekwelapheni nasekuvimbeleni uhla lwezifo zesikhunta ezihlaselayo, okuhlanganisa i-aspergillosis, i-fusariosis, i-chromoblastomycosis, i-mycetoma, ne-coccidiomycosis ezigulini ezingafuni, noma ezingabekezeleli, ukwelashwa okujwayelekile nge-amphotericin B kanye/noma i-itraconazole.E-US, kugunyazwe ukuvimbela izifo ze-Aspergillus kanye ne-Candida ezigulini ezineminyaka engu-13 ubudala ezisengozini enkulu yokuthola lezi zifo ngenxa yokuzivikela komzimba.Ukwengeza, kuvunyelwe ukwelashwa kwe-oropharyngeal candidiasis.I-Posaconazole inomsebenzi owandisiwe ngaphezu kwamanye amalungu e-azole antifungals.Ngaphezu komsebenzi onamandla omelene nezimo eziphikisayo ze-aspergillosis kanye ne-fluconazole-resistant Candida, ibonisa umsebenzi ngokumelene namaZygomycetes.I-Posaconazole iyisidakamizwa se-triazole antifungal esimakethwa e-United States ngabakwa-Schering-Plough ngaphansi kwegama lokuhweba elithi Noxafil.