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I-Pyridine-3-Sulfonyl Chloride CAS 16133-25-8 Purity ≥98.5% (GC) I-Vonoprazan Fumarat Intermediate Factory Isithombe Esifakiwe
  • I-Pyridine-3-Sulfonyl Chloride CAS 16133-25-8 Purity ≥98.5% (GC) I-Vonoprazan Fumarat Intermediate Factory

I-Pyridine-3-Sulfonyl Chloride CAS 16133-25-8 Purity ≥98.5% (GC) I-Vonoprazan Fumarat Intermediate Factory

Incazelo emfushane:

Igama Lekhemikhali: I-Pyridine-3-Sulfonyl Chloride

I-CAS: 16133-25-8

Ubumsulwa: ≥98.5% (GC)

Ukubukeka: Uketshezi Oluphuzi Olungenambala noma Oluphuzi

I-Intermediate ye-Vonoprazan Fumarate (CAS: 1260141-27-2)

Ikhwalithi Ephezulu, Ukukhiqizwa Kwezohwebo

E-Mail: alvin@ruifuchem.com


Imininingwane Yomkhiqizo

Imikhiqizo Ehlobene

Omaka bomkhiqizo

Incazelo:

Ukunikezela nge-Vonoprazan Fumarate kanye Nezimaphakathi Ezihlobene
5-(2-Fluorophenyl)pyrrole-3-Carboxaldehyde CAS 881674-56-2
I-Pyridine-3-Sulfonyl Chloride CAS 16133-25-8
I-Vonoprazan Fumarate (TAK-438) CAS 1260141-27-2 881681-01-2

Chemical Properties:

Igama Lekhemikhali I-Pyridine-3-Sulfonyl Chloride
Omqondofana 3-Pyridinesulfonyl Chloride;3-Pyridylsulfonyl Chloride;m-Pyridinesulfonyl Chloride;I-Piperidine-3-Sulfonylchloride
Inombolo ye-CAS 16133-25-8
Inombolo yeCAT I-RF-PI540
Isimo Sesitoko Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani
I-Molecular Formula I-C5H4ClNO2S
Isisindo samangqamuzana 177.61
Ibhrendi I-Ruifu Chemical

Imininingwane:

Into Imininingwane
Ukubukeka Uketshezi Oluphuzi Olungenambala noma Oluphuzi
Ukuhlanzeka / Indlela Yokuhlaziya ≥98.5% (GC)
Iphuzu elibilayo 110.0 ~ 112.0℃/2mm Hg
Ukungcola Okukodwa ≤0.50%
Ukungcola Okuphelele ≤1.5%
Izinga Lokuhlola I-Enterprise Standard
Ukusetshenziswa I-Intermediate ye-Vonoprazan Fumarate (CAS: 1260141-27-2)

Iphakheji nesitoreji:

Iphakheji: Ibhodlela, 25kg/Umgqomo, noma ngokwezidingo zekhasimende.

Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni nakumswakama.

Izinzuzo:

1

I-FAQ:

Isicelo:

I-Pyridine-3-Sulfonyl Chloride (i-CAS: 16133-25-8) iphakathi kwe-Vonoprazan Fumarate (CAS: 1260141-27-2).I-Vonoprazan Fumarate, eyatholwa futhi yathuthukiswa ngu-Takeda no-Otsuka, yagunyazwa yi-PMDA yaseJapane ngoDisemba 2014, futhi ikhonjiswe ekwelapheni isilonda sesisu, isilonda se-duodenal kanye ne-reflux esophagitis.I-Vonoprazan fumarate inomshini wokusebenza wenoveli obizwa ngokuthi i-potassium-competitive acid blockers, evimbela ngokuncintisana ukuboshwa kwama-ion e-potassium ku-H+, K+-ATPase (eyaziwa nangokuthi iphampu ye-proton) esinyathelweni sokugcina sokuphuma kwe-asidi esiswini kumaseli e-gastric parietal.I-Vonoprazan ayivimbeli umsebenzi we-Na+, K+-ATPase ngisho nasekugxiliseni izikhathi ezingu-500 ngaphezu kwamanani e-IC50 uma kuqhathaniswa nomsebenzi wesisu we-H+, K+-ATPase.Ngaphezu kwalokho, umuthi awuthintwa yi-gastric secretory state, ngokungafani nama-PPI.

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