(R)-(-)-3-Quinuclidinol CAS 25333-42-0 Ubumsulwa ≥99.0% Chiral Purity ≥99.0%

Incazelo emfushane:

Igama Lekhemikhali: (R)-(-)-3-Quinuclidinol

I-CAS: 25333-42-0

Ukubukeka: Impushana Emhlophe noma Engamhlophe

Ubumsulwa: ≥99.0%

Ukuhlanzeka kweChiral: ≥99.0%

I-Intermediate of API (CAS: 242478-38-2) ekwelapheni i-Overactive Bladder (Pollakiuria)

Enquiry: alvin@ruifuchem.com


Imininingwane Yomkhiqizo

Imikhiqizo Ehlobene

Omaka bomkhiqizo

Incazelo:

5

Chemical Properties:

Igama Lekhemikhali (R)-(-)-3-Quinuclidinol
Omqondofana (R)-3-Quinuclinol
Inombolo ye-CAS 25333-42-0
Inombolo yeCAT I-RF-CC117
Isimo Sesitoko Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani
I-Molecular Formula C7H13NO
Isisindo samangqamuzana 127.18
Ibhrendi I-Ruifu Chemical

Imininingwane:

Into Imininingwane
Ukubukeka Impushana Emhlophe noma Engamhlophe
I-Identification RT (by GC) Vumelana Nezinga Lereferensi
I-Melting Point 212.0~224.0℃
Ukuzungezisa Okuqondile [α]D20 -40.0°~ -48.0°
Umswakama (KF) ≤0.50%
Izinsalela ekushiseni ≤0.50%
Ubumsulwa ≥99.0%
Ukungcola Okuphelele ≤1.00%
I-Chiral Purity ≥99.0%
I-Enantiomer ≤1.00%
Isivivinyo 98.0%~101.0% (Kusisekelo Esingenamanzi)
Izinga Lokuhlola I-Enterprise Standard
Ukusetshenziswa I-Chiral Compounds;Pharmaceutical Intermediates

Iphakheji nesitoreji:

Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwemfuneko yekhasimende

Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni nakumswakama

Izinzuzo:

1

I-FAQ:

2

Isicelo:

I-Shanghai Ruifu Chemical Co., Ltd. ingumkhiqizi oholayo kanye nabaphakeli be-(R)-(-)-3-Quinuclidinol (CAS: 25333-42-0) enekhwalithi ephezulu, esetshenziswa kabanzi ku-organic synthesis, synthesis of pharmaceutical intermediates and I-Active Pharmaceutical Ingredient (API) synthesis.(R)-(-)-3-Quinuclidinol ingasetshenziswa njengendawo emaphakathi ekuhlanganisweni kwe-API (CAS: 242478-38-2).(CAS: 242478-38-2) umuthi we-antimuscarinic osetshenziselwa ukwelapha esinyeni esisebenza ngokweqile esibangela izimpawu zokuvama, ukuphuthuma, noma ukungakwazi ukuzibamba.(I-CAS: 242478-38-2) i-M3 muscarinic receptor antagonist eyakhiwe futhi yethulwa ukwelashwa kwesinye esisebenza ngokweqile (i-pollakiuria) eYurophu.I-M3 receptors iye yathinteka ekufinyezweni kwemisipha ebushelelezi ekhishwe yi-neurally yesinye, futhi ama-M2 receptors nawo asolwa ngokudlala indima ngenxa yokubusa kwawo ku-detrusor muscle.Ukuhlanganiswa kwe-solifenacin kuhilela ukulungiswa kwe-racemic 1-Phenyl-1,2,3,4-Tetrahydroisoquinoline nge-cyclization ye-N-(2-Phenylethyl)benzamide, kanye nokusabela okulandelayo nge-ethyl chloroformate kanye ne-transesterification nge-(R)-3-Quinuclidinol. .I-Chiral chromatography inikeza ukuhlukaniswa kwe-diastereomer oyifunayo.Kungenjalo, i-1-Phenyl-1,2,3,4-Tetrahydroisoquinoline ingase ibekwe ngaphansi kokuxazululwa kwe-optical (+) -Tartaric Acid ngaphambi kokwelashwa nge-ethyl chloroformate kanye ne-transesterification elandelayo.

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