(R)-Lansoprazole Dexlansoprazole CAS 138530-94-6 Assay 98.0~102.0% (HPLC) Isithombe Esifakiwe Sefekthri

(R)-Lansoprazole Dexlansoprazole CAS 138530-94-6 Assay 98.0~102.0% (HPLC) Factory

Incazelo emfushane:

Igama Lekhemikhali: (R)-Lansoprazole

Synonym: Dexlansoprazole

I-CAS: 138530-94-6

Isivivinyo: 98.0~102.0% (HPLC, %w/w)

Ukubukeka: I-Crystalline Powder Emhlophe ukuya Kokumhlophe

E-Mail: alvin@ruifuchem.com

Thumela i-imeyili kithi

Imininingwane Yomkhiqizo

Imikhiqizo Ehlobene

Omaka bomkhiqizo

Incazelo:

I-Ruifu Chemical Supply Lansoprazole Intermediates
I-Lansoprazole CAS 103577-45-3
I-Lansoprazole Chloride Compound CAS 127337-60-4
(R)-Lansoprazole Dexlansoprazole CAS 138530-94-6

Chemical Properties:

Igama Lekhemikhali	(R)-Lansoprazole
Omqondofana	R-(+)-Lansoprazole;I-Dexlansoprazole;2-[(R)-[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole;T 168390;I-TAK 390;Ukungcola kweLansoprazole 14;Ukungcola Okuhlobene Ne-Dexlansoprazole 2;(R) -2-[[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]methyl]sulfinyl]-1H-Benzimidazole;
Inombolo ye-CAS	138530-94-6
Inombolo yeCAT	I-RF-PI1916
Isimo Sesitoko	Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani
I-Molecular Formula	I-C16H14F3N3O2S
Isisindo samangqamuzana	369.36
Ibhrendi	I-Ruifu Chemical

Imininingwane:

Into	Imininingwane
Ukubukeka	I-Crystalline Powder emhlophe ukuya kokumhlophe
Ukuncibilika	I-Soluble ku-Dimethylformamide, Icishe Ayincibiliki Emanzini
Ukucaca Nombala Wesixazululo	Ihlangabezana Nemfuneko
Ukuhlonza IR	I-spectrum yokumuncwa kwe-infrared kufanele ihambisane nento eyireferensi
Ukuhlonza HPLC	Isikhathi sokugcina sesiqongo esiyinhloko kufanele sihambisane naleso sereferensi
Ukuzungezisa okuqondile	+142.0°～+149.0°
I-Melting Point	~ 140.0℃
Okuqukethwe kwamanzi (KF)	<1.00%
Izinsalela ekushiseni	<0.10%
Ukungcola Okuhlobene	(HPLC)
I-nitrogen oxides	<0.10%
Sulfone	<0.40%
I-Sulfidi	<0.20%
Noma Ikuphi Okunye Ukungcola Okukodwa	<0.10%
Ukungcola Okuphelele	<0.60%
I-Optical Purity (HPLC)	>99.5%
Isivivinyo	98.0~102.0% (HPLC, %w/w, kusisekelo se-anhydrous, i-solvent-free)
Izinsimbi Ezisindayo	<10ppm
Izincibilikisi Ezisele
I-Toluene	<890ppm
n-Heptane	<5000ppm
I-Endotoxin yebhaktheriya	<2.5EU/mg
Izinga Lokuhlola	I-USP Standard;I-Pharmacopoeia yaseShayina
Ukusetshenziswa	I-API;I-Olly Active Proton Pump Inhibitor

Iphakheji nesitoreji:

Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwemfuneko yekhasimende

Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni nakumswakama

Izinzuzo:

I-FAQ:

Isicelo:

(R)-Lansoprazole (CAS: 138530-94-6) iyi-R enantiomer ye-Lansoprazole, i-Lansoprazole (AG 1749) iyi-proton pump inhibitor esebenzayo ngomlomo evimbela isisu ekukhiqizeni i-asidi.I-Dexlansoprazole ye-Lansoprazole dextroisomer, iwuhlobo lwezidakamizwa ezilwa nesilonda se-peptic ezithathwe esikhundleni se-benzimidazole, esakhiweni samangqamuzana zibe isakhi se-fluorine, i-proton pump inhibitors yesibili i-omeprazole ngemva kwalokho.I-Dexlansoprazole inomphumela wokuvimbela ukukhishwa kwe-asidi yesisu, umphumela ungcono kunezinye izidakamizwa (i-Omeprazole, i-Pantoprazole, i-Rebela, i-Tetrazolium) ingavimbela kakhulu ukuvela kwesilonda.Ingcono kune-famotidine noma i-Omeprazole ngokulimala kwe-gastric mucosa eyenziwe ngotshwala kanye nesilonda se-duodenal ikakhulukazi okubangelwa i-acid hypersecretion.Ngaphezu kwalokho, umkhiqizo unomphumela ofanayo we-anti Helicobacter pylori njengokulungiswa kwe-bismuth, futhi usetshenziselwa i-reflux esophagitis kanye ne-Zhuo AI syndrome.I-Takeda Pharmaceuticals ithole ukugunyazwa kwe-dexlansoprazole, ukwakheka okumbaxambili kokukhululwa kwe-(R)-isomer ye-lansoprazol proton pump inhibitor (PPI) kakade emakethe, evela ku-FDA ngoJanuwari 2009. I-Dexlansoprazole iyikhepsuli yokukhululwa ebambezelekile yokwelashwa ngomlomo kanye ngosuku. Isilungulela esihambisana nesifo se-reflux ye-gastroesophageal (GERD), ukuphulukiswa kwe-erosive esophagitis (EE) kanye nokugcinwa kwe-EE epholile.