I-Ramelteon Acrylonitrile CAS 196597-79-2 Ramelteon Intermediate Purity >98.0% (HPLC)

Incazelo emfushane:

Igama Lekhemikhali: (E)-(1,6,7,8-Tetrahydro-2H-Indeno[5,4-b]furan-8-ylidene)acetonitrile

Synonym: Ramelteon Acrylonitrile

I-CAS: 196597-79-2

Ubumsulwa: >98.0% (HPLC)

Ukubukeka: Impushana Eqinile Emhlophe Kuya Kuphuzi

I-Intermediate of Ramelteon (CAS: 196597-26-9)

Thintana: UDkt. Alvin Huang

Iselula/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


Imininingwane Yomkhiqizo

Imikhiqizo Ehlobene

Omaka bomkhiqizo

Incazelo:

Chemical Properties:

Igama Lekhemikhali (E)-(1,6,7,8-Tetrahydro-2H-Indeno[5,4-b]furan-8-ylidene)i-acetonitrile
Omqondofana I-Ramelteon Acrylonitrile;Ukungcola kwe-Ramelteon 6;Ukungcola kwe-Ramelteon B;Ukungcola kwe-Ramelteon Cyano;(E)-2-(6,7-Dihydro-1H-Indeno[5,4-b]furan-8(2H)-ylidene)i-acetonitrile;(2E)-2-(1,2,6,7-Tetrahydrocyclopenta[e][1]benzofuran-8-ylidene)i-acetonitrile;(1,2,6,7-Tetrahydro-3-oxa-as-indacen-8-ylidene)-acetonitrile
Inombolo ye-CAS 196597-79-2
Inombolo yeCAT RF2886
Isimo Sesitoko Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani
I-Molecular Formula I-C13H11NO
Isisindo samangqamuzana 197.23
I-Melting Point 146.0 ~ 151.0℃
Iphuzu elibilayo 392.1±21.0℃ ku-760 mmHg
I-Flash Point 165.0±15.9℃
Ukuminyana 1.321±0.06 g/cm3
Ikhodi ye-HS 2932999099
Ibhrendi I-Ruifu Chemical

Imininingwane:

Into Imininingwane
Ukubukeka Impushana Eqinile Emhlophe Kuya Kuphuzi
Ukuhlanzeka / Indlela Yokuhlaziya >98.0% (HPLC)
Ukulahlekelwa Ekumisweni <1.00%
Ukungcola Okuphelele <2.00%
1 H NMR Spectrum Ihambisana Nesakhiwo
Izinga Lokuhlola I-Enterprise Standard
Ukusetshenziswa I-Intermediate of Ramelteon (CAS: 196597-26-9)

Iphakheji nesitoreji:

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Ukulethwa Okusheshayo: Uma kungaphakathi kwesitoko, ukulethwa kwezinsuku ezintathu kuqinisekisiwe

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Ikhwalithi Ephezulu: Kusungulwe uhlelo oluphelele lokuqinisekisa ikhwalithi

I-FAQ:

Indlela Yokuthenga?Sicela uxhumaneDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 

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IkhwalithiIsiqiniseko?Isistimu yokulawula ikhwalithi eqinile.Imishini yobuchwepheshe yokuhlaziya ifaka i-NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, NOMA, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, njll.

Amasampula?Imikhiqizo eminingi inikeza amasampula wamahhala wokuhlolwa kwekhwalithi, izindleko zokuthumela kufanele zikhokhelwe amakhasimende.

Ukuhlolwa Kwemboni?Wamukelekile ekucwaningweni kwemboni.Sicela wenze i-aphoyintimenti kusengaphambili.

I-MOQ?Ayikho i-MOQ.I-oda elincane liyamukeleka.

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Isicelo:

(E)-(1,6,7,8-Tetrahydro-2H-Indeno[5,4-b]furan-8-ylidene)i-acetonitrile (CAS: 935-56-8) iphakathi kwe-Ramelteon (CAS: 196597 -26-9).I-Ramelteon (TAK-375) iyinoveli ye-melatonin receptor agonist ye-MT1 yomuntu kanye ne-MT2 receptors kanye ne-chick forebrain melatonin receptors ene-Ki ye-14 pM, 112 pM kanye ne-23.1 pM, ngokulandelana.I-molecule ye-melatonin yashintshwa ngokuyinhloko ngokufaka i-nitrogen yeringi ye-indole ukuze inikeze indandatho ye-indane nangokuhlanganisa iqembu le-5-methoxyl eringini ye-indole ibe yindandatho ye-furan eqinile.Ukukhethwa kwe-ramelteon ewumphumela yesamukeli se-MT1 izikhathi eziyisishiyagalombili ngaphezu kwalokho kwesamukeli se-MT2.Ngokungafani ne-melatonin, iphumelela kakhulu ekuqaliseni ukulala (umsebenzi we-MT1)kunokulungisa isigqi sokujikeleza (umsebenzi we-MT2).Ibukeka iphumelela kakhulu kune-melatonin kodwa ingasebenzi kahle kune-benzodiazepines njenge-hypnotic.Okubalulekile, lesi sidakamizwa asinaso isibopho sokulutha (akusinto elawulwayo).Ngenxa yalokho, isanda kugunyazwa ukwelashwa kokuqwasha.

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