I-Ramelteon (TAK-375) CAS 196597-26-9 Ubumsulwa >99.5% (HPLC)

Incazelo emfushane:

Igama Lekhemikhali: Ramelteon

Amazwi afanayo: TAK-375;I-Rozerem®

CAS: 196597-26-9

Ubumsulwa: >99.5% (HPLC)

Ukubukeka: I-Crystalline Powder Emhlophe

I-API, Igunyazwe Ukwelashwa Kokuqwasha

Thintana: UDkt. Alvin Huang

Iselula/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

Thumela i-imeyili kithi

Imininingwane Yomkhiqizo

Imikhiqizo Ehlobene

Omaka bomkhiqizo

Incazelo:

Umkhiqizi Oholayo Nomhlinzeki, Abaphakathi kwe-Ramelteon
I-Ramelteon (TAK-375) CAS 196597-26-9
2,3-Dihydrobenzofuran CAS 496-16-2
1,2,6,7-Tetrahydro-8H-Indeno[5,4-b]furan-8-one CAS 196597-78-1
I-Ramelteon Acrylonitrile CAS 196597-79-2
I-Despropionyl Ramelteon Hydrochloride CAS 196597-80-5
2-(2,6,7,8-Tetrahydro-1H-Indeno[5,4-b]furan-8-yl)ethanamine Hydrochloride CAS 1053239-39-6
Please contact: alvin@ruifuchem.com

Chemical Properties:

Igama Lekhemikhali	I-Ramelteon
Omqondofana	(S)-N-[2-(2,6,7,8-Tetrahydro-1H-Indeno[5,4-b]furan-8-yl)ethyl]propionamide;I-TAK-375;I-TAK375;I-TAK 375;I-Rozerem
Inombolo ye-CAS	196597-26-9
Inombolo yeCAT	RF2885
Isimo Sesitoko	Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani
I-Molecular Formula	I-C16H21NO2
Isisindo samangqamuzana	259.35
I-Melting Point	113.0 ukuze 116.0 ℃
Iphuzu elibilayo	455.3±24.0℃
Ukuminyana	1.119±0.06 g/cm3
Ukuzungezisa Okuthile [α]20/D	-55.0° ukuya -60.0° (C=1, CHCL3)
Ukuncibilika Emanzini	Ayincibiliki emanzini (11 mg/l 25℃)
Ukuncibilika	I-Soluble ku-Ethanol, i-Methanol, i-DMSO
Ibhrendi	I-Ruifu Chemical

Imininingwane:

Into	Imininingwane
Ukubukeka	I-Crystalline Powder Emhlophe
Ukuhlanzeka / Indlela Yokuhlaziya	>99.5% (HPLC)
I-Melting Point	113.0~116.0℃
Ukulahlekelwa Ekumisweni	<0.50%
Izinsalela ekushiseni	<0.10%
Isomer Purity	<0.10%
Izinsimbi Ezisindayo	<10ppm
I-acidity noma i-alkalinity	Vumelanisa
I-Ethanol	<5000ppm
Ukungcola Okukodwa	<0.20%
Ukungcola Okuphelele	<0.50%
I-Infrared Spectrum	Ivumelana Nesakhiwo
Izinga Lokuhlola	I-Enterprise Standard
Ukusetshenziswa	I-API, Igunyazwe Ukwelashwa Kokuqwasha

Iphakheji nesitoreji:

Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwemfuneko yekhasimende

Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni nakumswakama

Izinzuzo:

Amandla Anele: Izinsiza ezanele kanye nochwepheshe

Isevisi Yobuchwepheshe: Isevisi yokuthenga yokuma eyodwa

Iphakheji le-OEM: Iphakheji yangokwezifiso kanye nelebula iyatholakala

Ukulethwa Okusheshayo: Uma kungaphakathi kwesitoko, ukulethwa kwezinsuku ezintathu kuqinisekisiwe

Impahla Ezinzile: Gcina isitoko esinengqondo

Ukusekelwa Kwezobuchwepheshe: Isixazululo sezobuchwepheshe siyatholakala

Isevisi Yokuhlanganisa Ngokwezifiso: Isukela kumagremu kuye kumakhilo

Ikhwalithi Ephezulu: Kusungulwe uhlelo oluphelele lokuqinisekisa ikhwalithi

I-FAQ:

Indlela Yokuthenga?Sicela uxhumaneDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com

Iminyaka engu-15 Yokuhlangenwe nakho?Sinesipiliyoni seminyaka engaphezu kwe-15 ekwakhiweni nasekuthumeleni kwamanye amazwe uhla olubanzi lwezinga eliphezulu lokuxhumanisa imithi noma amakhemikhali amahle.

Izimakethe Eziyinhloko?Thengisa emakethe yasekhaya, eNyakatho Melika, eYurophu, eNdiya, eKorea, eJapane, e-Australia, njll.

Izinzuzo?Ikhwalithi ephezulu, intengo ethengekayo, izinsizakalo ezichwepheshile nokusekelwa kobuchwepheshe, ukulethwa okusheshayo.

IkhwalithiIsiqiniseko?Isistimu yokulawula ikhwalithi eqinile.Imishini yobuchwepheshe yokuhlaziya ifaka i-NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, NOMA, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, njll.

Amasampula?Imikhiqizo eminingi inikeza amasampula wamahhala wokuhlolwa kwekhwalithi, izindleko zokuthumela kufanele zikhokhelwe amakhasimende.

Ukuhlolwa Kwemboni?Wamukelekile ekucwaningweni kwemboni.Sicela wenze i-aphoyintimenti kusengaphambili.

I-MOQ?Ayikho i-MOQ.I-oda elincane liyamukeleka.

Isikhathi sokuthumela? Uma kungaphakathi kwesitoko, ukulethwa kwezinsuku ezintathu kuqinisekisiwe.

Ezokuthutha?By Express (FedEx, DHL), by Air, by Sea.

Amadokhumenti?Ngemuva kwenkonzo yokuthengisa: I-COA, i-MOA, i-ROS, i-MSDS, njll.

Custom Synthesis?Ingahlinzeka ngezinsizakalo zokwenziwa ngokwezifiso ukuze zilingane kangcono nezidingo zakho zocwaningo.

Imigomo Yokukhokha?I-invoyisi ye-Proforma izothunyelwa kuqala ngemva kokuqinisekiswa kwe-oda, kufakwe nemininingwane yethu yasebhange.Inkokhelo nge-T/T (Telex Transfer), PayPal, Western Union, njll.

Isicelo:

I-Ramelteon (CAS: 196597-26-9) yagunyazwa okokuqala yi-US Food and Drug Administration (FDA) ngoJulayi 22, 2005, yase yavunyelwa i-Pharmaceuticals and Medical Devices Agency (PMDA) ngomhla ka-Apr 16, 2010. Yasungulwa futhi imakethwe njenge-Rozerem® ngu-Takeda,ingasetshenziswa ukwelapha ukuqwasha ngobunzima bokulala, futhi inemiphumela eqondile ekuqwaleni okungapheli kanye nokuqwasha kwesikhashana.Lo mkhiqizo ungavula ngokukhetha uhlobo loku-1 bese uthayipha u-2 wama-receptors e-melatonin (MT1, MT2), ukhuphule ukulala kwegagasi elihamba kancane (SWS) kanye nokulala kokunyakaza kwamehlo okusheshayo (REW), ngaleyo ndlela kunciphise ukuqwasha.I-Ramelteamide umuthi wokuqala ongawumlutha wokwelapha ukuqwasha ongekho ngaphansi kokulawulwa okukhethekile.Lo mkhiqizo uyi-agonist ye-melatonin receptor.Inobudlelwane obuphezulu nama-melatonin MT1 kanye nama-MT2 receptors, futhi inomthelela othize futhi ophelele we-agonistic kuma-receptors e-MT1 kanye ne-MT2, kodwa ayihlanganisi nesamukeli se-MT3.Ngaphezu kwalokho, ayibophezeli kuma-neurotransmitter receptors njenge-GABA receptor complexes, futhi ayiphazamisi umsebenzi wama-enzyme amaningi ngaphakathi kwebanga elithile.Ngakho-ke, ingagwema ukuphazamiseka okuhlobene nezidakamizwa ze-GABA (ezingabangela izingozi zemoto, ukuwa nokuphuka).Njll.) kanye nokuba umlutha wezidakamizwa nokuncika.I-Rozerem® iyatholakala njengethebhulethi ehlanganiswe nefilimu ukuze isetshenziswe ngomlomo, equkethe u-8 mg we-Ramelteon yamahhala.Umthamo wabantu abadala onconywayo ngu-8 mg othathwe phakathi nemizuzu engama-30 yokulala.