I-Ramelteon Intermediate CAS 196597-78-1 Ubumsulwa >98.5% (HPLC)

Incazelo emfushane:

Igama: 1,2,6,7-Tetrahydro-8H-Indeno[5,4-b]furan-8-one

Synonimes: 6,7-Dihydro-1H-Indeno[5,4-b]furan-8(2H)-one

I-CAS: 196597-78-1

Ubumsulwa: >98.5% (HPLC)

Ukubukeka: Impushana Eqinile Emhlophe Ukuya Kuphuzi Okuphaphathekile

I-Intermediate of Ramelteon (CAS: 196597-26-9)

Ikhwalithi Ephezulu, Ukukhiqizwa Kwezohwebo

Thintana: UDkt. Alvin Huang

Iselula/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


Imininingwane Yomkhiqizo

Imikhiqizo Ehlobene

Omaka bomkhiqizo

Incazelo:

Chemical Properties:

Igama Lekhemikhali 1,2,6,7-Tetrahydro-8H-indeno[5,4-b]furan-8-one
Omqondofana 6,7-Dihydro-1H-Indeno[5,4-b]furan-8(2H) -enye;I-Ramelteon Ephakathi 1;Ramelteon I
Ukungcola Ramelteon Ukungcola A
Inombolo ye-CAS 196597-78-1
Inombolo yeCAT RF2883
Isimo Sesitoko Esitokweni, Amandla Okukhiqiza Amathani angama-20 ngenyanga
I-Molecular Formula I-C11H10O2
Isisindo samangqamuzana 174.20
I-Melting Point 133.0 ukuze 137.0 ℃
Iphuzu elibilayo 334.2±42.0℃
Ukuminyana 1.288±0.06 g/cm3
I-Hazard Class Iyacasula
Ibhrendi I-Ruifu Chemical

Imininingwane:

Into Imininingwane
Ukubukeka Impushana Eqinile Emhlophe Kuya Kuphuzi Ephuzi
Ukuhlanzeka / Indlela Yokuhlaziya >98.5% (HPLC)
I-Melting Point 133.0 ukuze 137.0 ℃
Amanzi (nguKarl Fischer) <0.50%
Izinsalela ekushiseni <0.10%
Ukungcola Okuphelele <1.50%
1 H NMR Spectrum Ihambisana Nesakhiwo
Izinga Lokuhlola I-Enterprise Standard
Ukusetshenziswa I-Intermediate of Ramelteon (CAS: 196597-26-9)

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Ukulethwa Okusheshayo: Uma kungaphakathi kwesitoko, ukulethwa kwezinsuku ezintathu kuqinisekisiwe

Impahla Ezinzile: Gcina isitoko esinengqondo

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Ikhwalithi Ephezulu: Kusungulwe uhlelo oluphelele lokuqinisekisa ikhwalithi

I-FAQ:

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Isicelo:

I-1,2,6,7-Tetrahydro-8H-indeno[5,4-b]furan-8-one (CAS: 196597-78-1) isetshenziswa njengendawo ephakathi ye-Ramelteon (CAS: 196597-26-9) , i-nucleus engumama yokuhlanganisa i-Ramelteon.I-Ramelteon ingeyokuqala ekilasini elisha lama-ejenti okulala abophezela ngokukhetha kuma-MT1 kanye ne-MT2 receptors ku-nucleus ye-suprachiasmatic (SCN), esikhundleni sokubophezela kuma-receptors e-GABA.I-Ramelteon ayibonisi noma yikuphi ukubopha okuncomekayo kuma-GABAA receptors, ahlotshaniswa ne-anxiolytic, myorelaxant, nemiphumela ye-amnesic.I-Ramelteon ingasetshenziselwa ukuqwasha, ikakhulukazi ukubambezeleka kokulala kokuqala.I-Ramelteon ayizange iboniswe ukuthi ikhiqiza ukuncika futhi ayizange ibonise amandla okuhlukumeza, futhi ukuhoxiswa nokuqwasha okuphindaphindiwe okujwayelekile ngamamoduli e-GABA akukho ku-ramelteon.Abanye odokotela basebenzisa i-ramelteon ekwelapheni i-Delayed sleep phase syndrome.Ukwelapha ukuqwasha (inkinga yokulala).Ingase futhi isetshenziselwe ezinye izimo njengoba kunqunywe udokotela wakho.URamelteon ungumphikisi we-melatonin.Isebenza ngokusebenza kuma-melatonin receptors ebuchosheni, okusiza ukuthi ulale.

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