I-Remdesivir Intermediate CAS 1354823-36-1 COVID-19 N-[(S)-(4-nitrophenoxy)phenoxyphosphinyl]-L-Alanine 2-ethylbutyl ester

Incazelo emfushane:

N-[(S)-(4-nitrophenoxy)phenoxyphosphinyl]-L-Alanine 2-ethylbutyl ester

I-CAS: 1354823-36-1

I-Intermediate ye-Remdesivir (CAS 1809249-37-3) yokwelashwa kwe-COVID-19

Ikhwalithi Ephezulu, Ukukhiqizwa Kwezohwebo

Inquiry: alvin@ruifuchem.com

Thumela i-imeyili kithi

Imininingwane Yomkhiqizo

Imikhiqizo Ehlobene

Omaka bomkhiqizo

Incazelo:

Umkhiqizi Wokuhlinzeka Ngempahla Yezohwebo i-Remdesivir kanye Nezixhumanisi Ezihlobene Nekhwalithi Ephezulu
I-Remdesivir CAS 1809249-37-3
2-Ethyl-1-butanol CAS 97-95-0
I-Trimethylsilyl Cyanide CAS 7677-24-9
I-4-Nitrophenol CAS 100-02-7
2-Ethylbutyl ((S)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate CAS 1911578-98-7
N-[(S)-(4-nitrophenoxy)phenoxyphosphinyl]-L-Alanine 2-ethylbutyl ester CAS 1354823-36-1
(S)-2-Ethylbutyl 2-Aminopropanoate Hydrochloride CAS 946511-97-3
I-Remdesivir Metabolite (GS-441524) CAS 1191237-69-0
I-Remdesivir N-2 I-CAS Emaphakathi 1191237-80-5
2,3,5-Tri-O-benzyl-D-ribonolactone CAS 55094-52-5
7-Bromopyrrolo[2,1-f][1,2,4]triazin-4-amine CAS 937046-98-5
I-Pyrrolo[1,2-F][1,2,4]Triazin-4-Amine CAS 159326-68-8
4-Amino-7-iodopyrrolo[2,1-f][1,2,4]triazine CAS 1770840-43-1

Chemical Properties:

Igama Lekhemikhali	N-[(S)-(4-nitrophenoxy)phenoxyphosphinyl]-L-Alanine 2-ethylbutyl ester
Omqondofana	I-Remdesivir Intermediate;I-Remdesivir Side Chain;I-Remdesivir p-NitroPhenoxy L-Alanine Ukungcola;I-Remdesivir Ukungcola 4;I-Remdesivir-002;(S)-2-Ethylbutyl 2-((S)-(4-nitrophenoxy)(phenoxy)-phosphoryl)-amino)propanoate
Inombolo ye-CAS	1354823-36-1
Inombolo yeCAT	I-RF-PI297
Isimo Sesitoko	Esitokweni, Isikali Sokukhiqiza Sifika Emakhulwini Amakhilogremu
I-Molecular Formula	I-C21H27N2O7P
Isisindo samangqamuzana	450.42
Ibhrendi	I-Ruifu Chemical

Imininingwane:

Into	Imininingwane
Ukubukeka	Impushana Emhlophe Kuya Kucishe Emhlophe
Ukuhlonza	IR, HPLC
Ukulahlekelwa Ekumisweni	≤1.0%
Ukungcola Okukodwa	≤0.50%
Izinsimbi Ezisindayo	≤20ppm
Ubumsulwa	≥98.0%
Izinga Lokuhlola	I-Enterprise Standard
Ukusetshenziswa	I-Intermediate ye-Remdesivir (CAS 1809249-37-3);I-COVID 19

Iphakheji nesitoreji:

Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, isigubhu seCardboard, 25kg/Drum, noma ngokwezidingo zekhasimende.

Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni, umswakama kanye nezinambuzane.

Izinzuzo:

I-FAQ:

Isicelo:

I-N-[(S)-(4-nitrophenoxy)phenoxyphosphinyl]-L-Alanine 2-ethylbutyl ester (CAS 1354823-36-1, eyaziwa nangokuthi i-Remdesivir Ukungcola 4) i-sidechain ye-phosphoramidate ngokuvamile esetshenziselwa ukulungiswa kwe-Remdesivir (CAS 1809249-37-3, GS-5734), okuwumuthi ophenywayo we-antiviral inoveli owaqala ukwelapha isifo segciwane le-Ebola kanye nokutheleleka ngegciwane le-Marburg futhi okubuye kwatholakala ukuthi ukhombisa umsebenzi wokulwa namagciwane ngokumelene nama-coronavirus (isb. SARS-Cov-2/ I-COVID-19).Ngesikhathi sokuqubuka kwesifo esisha seCoronavirus sika-2019 (COVID-19), i-Remdesivir (CAS 1809249-37-3) ingomunye wemikhiqizo yocwaningo ehlobene ne-COVID-19.I-Remdesivir, ethengiswa ngaphansi kwegama lomkhiqizo i-Veklury, umuthi ovimbela amagciwane obanzi owenziwe yinkampani ye-biopharmaceutical Gilead Sciences.Ilawulwa ngomjovo emithanjeni.Ngesikhathi sobhubhane lwe-COVID-19, i-Remdesivir yagunyazwa noma yagunyazwa ukusetshenziswa okuphuthumayo ukwelapha i-COVID-19 emazweni acishe abe ngu-50.Imihlahlandlela ebuyekeziwe evela ku-World Health Organization ngoNovemba 2020 ihlanganisa isincomo esinemibandela ngokumelene nokusetshenziswa kwe-Remdesivir ekwelapheni i-COVID-19.