I-Remdesivir Intermediate CAS 1911578-98-7 2-Ethylbutyl ((S)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate

Incazelo emfushane:

Igama Lekhemikhali: 2-Ethylbutyl ((S)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate

CAS: 1911578-98-7

Ukubukeka: Impushana Emhlophe ukuya EmhlopheUbumsulwa: ≥98.0%

I-Intermediate ye-Remdesivir (CAS 1809249-37-3) COVID-19

Ikhwalithi Ephezulu, Ukukhiqizwa Kwezohwebo

Inquiry: alvin@ruifuchem.com

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Incazelo:

Umkhiqizi Wokuhlinzeka Ngempahla Yezohwebo i-Remdesivir kanye Nezixhumanisi Ezihlobene Nekhwalithi Ephezulu
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2-Ethyl-1-butanol CAS 97-95-0
I-Trimethylsilyl Cyanide CAS 7677-24-9
I-4-Nitrophenol CAS 100-02-7
2-Ethylbutyl ((S)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate CAS 1911578-98-7
N-[(S)-(4-nitrophenoxy)phenoxyphosphinyl]-L-Alanine 2-ethylbutyl ester CAS 1354823-36-1
(S)-2-Ethylbutyl 2-Aminopropanoate Hydrochloride CAS 946511-97-3
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I-Remdesivir N-2 I-CAS Emaphakathi 1191237-80-5
2,3,5-Tri-O-benzyl-D-ribonolactone CAS 55094-52-5
7-Bromopyrrolo[2,1-f][1,2,4]triazin-4-amine CAS 937046-98-5
I-Pyrrolo[1,2-F][1,2,4]Triazin-4-Amine CAS 159326-68-8
4-Amino-7-iodopyrrolo[2,1-f][1,2,4]triazine CAS 1770840-43-1

Chemical Properties:

Igama Lekhemikhali	2-Ethylbutyl ((S)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate
Omqondofana	N-[(S)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-L-Alanine 2-ethylbutyl ester;I-Remdesivir Intermediate;I-Remdesivir-001;I-Remdesivir Ukungcola 21
Inombolo ye-CAS	1911578-98-7
Inombolo yeCAT	I-RF-PI303
Isimo Sesitoko	Esitokweni, Isikali Sokukhiqiza Sifika Emakhulwini Amakhilogremu
I-Molecular Formula	I-C21H27N2O7P
Isisindo samangqamuzana	495.38
Ukuminyana	1.2g/cm3
I-Melting Point	92.0~96.0℃(lit.)
Iphuzu elibilayo	356.7℃ ku-760 mmHg
Isimo Sokuthumela	Kuthunyelwe Ngaphansi Kwezinga Lokushisa Le-Ambient
Ibhrendi	I-Ruifu Chemical

Imininingwane:

Into	Imininingwane
Ukubukeka	Impushana Emhlophe Kuya Kumhlophe
I-Infrared Spectrum	Ivumelana Nesakhiwo
Ubumsulwa	≥99.0%
Ukulahlekelwa Ekumisweni	≤0.50%
Ukungcola Okukodwa	≤0.50%
Ukungcola Okuphelele	≤1.0%
Izinsimbi Ezisindayo	≤20ppm
Izinga Lokuhlola	I-Enterprise Standard
Ukusetshenziswa	I-Intermediate ye-Remdesivir (CAS 1809249-37-3)

Iphakheji nesitoreji:

Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, isigubhu seCardboard, 25kg/Drum, noma ngokwezidingo zekhasimende.

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Isicelo:

I-2-Ethylbutyl ((S)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate (CAS 1911578-98-7) iwukhiye ophakathi nendawo ekulungiseleleni ama-analogue ahlobene ne-Remdesivir.I-Remdesivir iyi-monophosphoramidate prodrug ye-adenosine analog, iyi-ejenti yophenyo ebanzi ye-antiviral enomsebenzi we-in vitro ngokumelene ne-SARS coronavirus, i-MERS coronavirus futhi, muva nje, i-Covid-19.I-Remdesivir yathuthukiswa kakhulu njengendlela yokwelapha izifo ze-filovirus njenge-Ebola virus virus noma i-Marburg virus.Kamuva, i-Remdesivir yatholakala ikhombisa umsebenzi wokulwa namagciwane ngokumelene namanye amagciwane e-RNA anentambo eyodwa njengegciwane lokuphefumula, i-Nipah virus, i-Hendra virus, i-Junin virus, igciwane le-Lassa fever kanye nama-coronavirus (okubandakanya amagciwane we-MERS kanye ne-SARS).Muva nje isacwaningwa njengomuthi othembisayo wokwelapha i-COVID-19 (igciwane elisha lohlobo lwe-SARS).I-Remdesivir, ethuthukiswe iSayensi yaseGileyadi, iwumkhiqizo we-adenosine oshintshashintsha ube yifomu elisebenzayo i-GS-441524 ephazamisa ukusebenza kwe-RNA polymerase encike ku-RNA esekelwe kugciwane futhi igweme ukuhlolwa kokuhlolwa nge-viral exoribonuclease (ExoN), okubangela ukwehla kokukhiqizwa kwe-RNA yegciwane.