I-Remdesivir Metabolite (GS-441524) CAS 1191237-69-0 COVID-19
Umkhiqizi Wokuhlinzeka Ngempahla Yezohwebo i-Remdesivir kanye Nezixhumanisi Ezihlobene Nekhwalithi Ephezulu
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Omqondofana | GS-441524;I-Remdesivir Metabolite;I-Remdesivir Intermediate;I-Nucleosid ye-Remdesivir;I-EVO984;I-Remdesivir O-Desphosphate Analogue;Inhlanganisela Ehlobene Ne-Remdesivir 6 Ukungcola |
Inombolo ye-CAS | 1191237-69-0 |
Inombolo yeCAT | I-RF-PI299 |
Isimo Sesitoko | Esitokweni, Isikali Sokukhiqiza Sifika Emakhulwini Amakhilogremu |
I-Molecular Formula | I-C12H13N5O4 |
Isisindo samangqamuzana | 291.26 |
Ukuncibilika | I-Soluble ku-DMSO |
Isitoreji | Indawo Eyomile Epholile |
Isimo Sokuthumela | Kuthunyelwe Ngaphansi Kwezinga Lokushisa Le-Ambient |
Ibhrendi | I-Ruifu Chemical |
Into | Imininingwane |
Ukubukeka | Impushana Emhlophe Kuya Kucishe Emhlophe |
Ubumsulwa | ≥99.0% |
I-Alpha-Isomer | ≤0.30% |
I-O-Bn Derivative | ≤0.30% |
Okuphuma ku-N-Bn | ≤0.30% |
Ukungcola Okukodwa Okukhulu | ≤0.30% |
Ukulahlekelwa Ekumisweni | ≤1.0% |
Izinsalela ekushiseni | ≤0.50% |
Izinsimbi Ezisindayo | ≤20ppm |
I-Arsenic | ≤2ppm |
Izinga Lokuhlola | I-Enterprise Standard |
Ukusetshenziswa | I-Intermediate ye-Remdesivir (CAS 1809249-37-3);I-COVID 19 |
Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, isigubhu seCardboard, 25kg/Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni, umswakama kanye nezinambuzane.
I-Remdesivir nucleoside analogue (GS-441524, CAS 1191237-69-0) iyibhulokhi yokwakha ebalulekile ekuhlanganisweni kwe-Remdesivir triphosphate (1355149-45-9) ne-Remdesivir (1809249-37-3).I-GS-441524 iyisidakamizwa se-nucleoside analogue antiviral eyakhiwa iSayensi yaseGileyadi.Le analog ye-phosphorus ngokuyinhloko iyinhlanganisela esebenzayo ekwelapheni i-Ebola ne-COVID-19.Iyi-plasma metabolite eyinhloko ye-antiviral prodrug remdesivir, futhi inengxenye yempilo cishe yamahora angama-24 ezigulini ezingabantu.I-Remdesivir kanye ne-GS-441524 zombili zitholwe zisebenza ngempumelelo ku-vitro ngokumelene nezinhlobo ze-feline coronavirus ezibhekene ne-feline infectious peritonitis (FIP), isifo esibulalayo esithinta amakati afuywayo.