I-Roflumilast CAS 162401-32-3 Assay 99.0~101.0% API

Incazelo emfushane:

Igama Lekhemikhali: Roflumilast

I-CAS: 162401-32-3

I-Assay: 99.0~101.0% (Ibalwa Ngesisekelo Esomisiwe)

Ukubukeka: I-Crystalline Powder Emhlophe noma Cishe Emhlophe

I-API PDE-4 Inhibitor COPD

Thintana: UDkt. Alvin Huang

Iselula/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

Thumela i-imeyili kithi

Imininingwane Yomkhiqizo

Imikhiqizo Ehlobene

Omaka bomkhiqizo

Incazelo:

I-Ruifu Chemical Supply Roflumilast Intermediates:
I-Roflumilast CAS 162401-32-3
4-Amino-3,5-Dichloropyridine CAS 22889-78-7

Chemical Properties:

Igama Lekhemikhali	I-Roflumilast
Omqondofana	3-(Cyclopropylmethoxy)-N-(3,5-Dichloropyridin-4-yl)-4-(Ddifluoromethoxy)benzamide
Inombolo ye-CAS	162401-32-3
Inombolo yeCAT	I-RF-PI2075
Isimo Sesitoko	Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani
I-Molecular Formula	I-C17H14Cl2F2N2O3
Isisindo samangqamuzana	403.21
Ukuminyana	1.471±0.060 g/cm3
Ukuzwela	Ukushisa Kuyazwela
Ibhrendi	I-Ruifu Chemical

Imininingwane:

Into	Imininingwane
Ukubukeka	I-Crystalline Powder Emhlophe noma Cishe Emhlophe
Ukuncibilika	I-soluble yamahhala ku-acetone, inyibilika kancane ku-acetronitrile, ayincibiliki kancane ku-ethanol e-anhydrous, cishe ayincibiliki emanzini.
I-Melting Point	157.0~162.0℃
Ukulahlekelwa Ekumisweni	<0.50%
Izinsalela ekushiseni	≤0.10%
Izinsimbi Ezisindayo	≤10ppm
I-Chloride	≤0.01%
Ukuhlonza A. UV	Ubude begagasi bokumuncwa okuphezulu kufanele bube ku-213~251nm
Ukuhlonza B. IR	I-spectrum yokumuncwa kwe-IR yesampula ihambisana naleyo yereferensi
Ukuhlonza C.	Ibonisa ukusabela kweFluoride
Izinto Ezihlobene
Ukungcola Okukodwa	≤0.10%
Ukungcola Okuphelele	<0.50%
Izincibilikisi Ezisele
I-Tert-Butanol	<0.10%
I-Tetrahydrofuran	<0.072%
I-Toluene	<0.089%
I-N, N-Dimethylformamide	<0.088%
Isivivinyo	99.0~101.0% (Ibalwe Ngesisekelo Esomisiwe)
Izinga Lokuhlola	I-Enterprise Standard
Ukusetshenziswa	I-API;I-COPD

Iphakheji nesitoreji:

Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwemfuneko yekhasimende

Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni nakumswakama

Izinzuzo:

I-FAQ:

Isicelo:

I-Roflumilast (i-CAS: i-162401-32-3) i-oral phosphodiesterase-4 (PDE-4) inhibitor ekhethiwe kanye ne-benzamide compound.Yasungulwa yinkampani yaseJalimane i-Altana ngo-1993 futhi iyona kuphela inhibitor yomlomo ye-PDE-4 esetshenziselwa ukwelapha izifo zemigudu yokuphefumula evunyelwe ukudayiswa.I-Roflumilast umuthi wokuqala wohlobo lwayo ukukhomba isifo esiyingozi esingalapheki esivimbela amaphaphu (COPD), futhi iphinde ibe umuthi wokuqala womlomo wokulwa nokuvuvukala owenzelwe iziguli ezine-COPD.Izakhiwo zayo eziyingqayizivele zingasiza ekulawuleni i-COPD: uma isetshenziswa ngokuhambisana nama-bronchodilator ekwelapheni iziguli ezinzima kakhulu ze-COPD, i-Roflumilast ingaba nenzuzo yokuqhubeka nokunciphisa izimpawu kanye nezinga lokuwohloka, ngaleyo ndlela iyenze ibe umuthi wokuqala oqondiswe ezigulini ezine-phenotype-spAecific COPD ewohlokayo eqhubekayo. kanye nokuphazamiseka okukhulu kokugeleza komoya okuhlobene nokukhwehlela okungapheli kanye ne-phlegm eyeqile.Ngaphandle kokuba ukwelashwa kwe-COPD enzima, i-Roflumilast ingase futhi isetshenziselwe ukuvimbela nokwelapha izifo zepheshana lokuphefumula kwemfuyo, ukukhwehlela okweqile kwe-mucosa bronchitis, i-asthmatic bronchitis, ne-acute bronchitis kanye ne-air sacculitis ehambisana nokuphuma kwepheshana lokuphefumula okungavamile.