(S)-1-Boc-3-Hydroxypiperidine CAS 143900-44-1 Ibrutinib Intermediate Purity >99.0% (GC)

Incazelo emfushane:

Igama Lekhemikhali: (S)-1-Boc-3-Hydroxypiperidine

I-CAS: 143900-44-1

I-Chiral Purity: >99.0% (GC)

Ukuhlanzeka Kwamakhemikhali: >99.0% (GC)

Ukubukeka: Impushana Emhlophe noma Amakristalu

I-Ibrutinib emaphakathi (CAS: 936563-96-1)

Ikhwalithi Ephezulu, Ukukhiqizwa Kwezohwebo

E-Mail: alvin@ruifuchem.com

Thumela i-imeyili kithi

Imininingwane Yomkhiqizo

Imikhiqizo Ehlobene

Omaka bomkhiqizo

Incazelo:

Chemical Properties:

Igama Lekhemikhali	(S)-1-Boc-3-Hydroxypiperidine
Omqondofana	(S)-1-(tert-Butoxycarbonyl)-3-Hydroxypiperidine;(S)-1-Boc-3-Piperidinol
Inombolo ye-CAS	143900-44-1
Inombolo yeCAT	I-RF-CC299
Isimo Sesitoko	Esitokweni, Amandla Okukhiqiza Amathani angama-20/Inyanga
I-Molecular Formula	I-C10H19NO3
Isisindo samangqamuzana	201.27
I-Melting Point	52.0 ~ 56.0℃
Ukuncibilika	I-Soluble ku-Methanol
Ukuzungezisa Okuthile [a]20/D	+9.0°~+11.0° (C=1 nge-Chloroform)
Ibhrendi	I-Ruifu Chemical

Imininingwane:

Into	Imininingwane
Ukubukeka	Impushana Emhlophe noma Amakristalu
I-Chiral Purity	>99.5% (GC)
I-Chemical Purity	>99.5% (GC)
Amanzi (KF)	≤0.50%
I-Methanol (GC)	≤50ppm
I-Ethanol (GC)	≤50ppm
I-DCM (GC)	≤500ppm
3-Hydroxypiperidine	≤0.10%
3-Hydroxypyridine	≤0.20%
1-Boc-3-Piperidone	≤0.10%
I-1-Boc-4-Hydroxypiperidine	≤0.10%
1.96 RRT	≤0.20%
Noma Ikuphi Ukungcola Okungashiwongo	≤0.10%
Izinga Lokuhlola	I-Enterprise Standard
Ukusetshenziswa	Abalamuli Bezemithi;I-Chiral Compounds

Iphakheji nesitoreji:

Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwezidingo zekhasimende.

Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni nakumswakama.

Izinzuzo:

I-FAQ:

Isicelo:

(S)-1-Boc-3-Hydroxypiperidine (i-CAS: 143900-44-1) i-chiral ebalulekile ephakathi kokuhlanganiswa kwe-Ibrutinib (CAS: 936563-96-1).I-Ibrutinib iwuhlobo lwe-Bruton tyrosine kinase (BTK) inhibitor, ingasetshenziselwa ukwelapha i-lymphocytic leukemia (CLL) kanye ne-mantle cell lymphoma (MCL).I-MCL ne-CLL kungokwe-B-cell non-Hodgkin's lymphoma, okunzima ukuyelapha futhi kulula ukuphindeka ngayo.I-chemical immunotherapy evamile ayinakho ukukhomba, ngokuvamile kwenzeka 3 noma 4 ukusabela okubi.I-Ibrutinib ne-B lymphocyte ingakhomba nge-BTK edingekayo ekwakhekeni, ukuhlukaniswa, nokudluliselwa kolwazi, ivimbele umsebenzi we-BTK ngendlela engenakuhlehliswa, futhi ivimbele ukwanda kwamangqamuzana esimila kanye nokuphila ngempumelelo.I-Ibrutinib ingamuncwa ngokushesha ngemva kokuphathwa ngomlomo, ngesikhathi se-1 ~ 2h ifinyelele ekugxilweni okuphezulu kwegazi, ukusabela okungalungile kungokweyodwa noma ezimbili, ngakho-ke, i-Ibrutinib izoba ukukhetha okusha kokwelashwa kwe-CLL ne-MCL.