(S)-1,2,3,4-Tetrahydro-1-Naphthoic Acid CAS 85977-52-2 Purity ≥99.0% ee≥99.0% Palonosetron Hydrochloride Intermediate Factory Isithombe Esifakiwe

(S)-1,2,3,4-Tetrahydro-1-Naphthoic Acid CAS 85977-52-2 Purity ≥99.0% ee≥99.0% I-Palonosetron Hydrochloride Intermediate Factory

Incazelo emfushane:

Igama Lekhemikhali: (S)-1,2,3,4-1-Tetrahydro-Naphthoic Acid

I-CAS: 85977-52-2

Ukubukeka: I-Crystalline Powder Emhlophe noma Cishe Emhlophe

Ubumsulwa: ≥99.0%

I-Enantimoer Excess: ee≥99.0%

I-Intermediate ye-Palonosetron Hydrochloride (CAS: 135729-62-3) ekwelapheni kwe-CINV

E-mail: alvin@ruifuchem.com

Thumela i-imeyili kithi

Imininingwane Yomkhiqizo

Imikhiqizo Ehlobene

Omaka bomkhiqizo

Incazelo:

I-Commercial Supply Palonosetron Hydrochloride kanye Nezixhumanisi Ezihlobene:
(S)-1,2,3,4-Tetrahydro-1-Naphthoic Acid CAS: 85977-52-2
(R)-1,2,3,4-Tetrahedro-1-Naphthoic Acid CAS: 23357-47-3
(S)-3-Aminoquinuclidine Dihydrochloride CAS: 119904-90-4
I-3-Quinuclidinone Hydrochloride CAS: 1193-65-3
I-1-Naphthoic Acid CAS: 86-55-5
I-Palonosetron Hydrochloride CAS: 135729-62-3 API

Chemical Properties:

Igama Lekhemikhali	(S)-1,2,3,4-Tetrahydro-1-Naphthoic Acid
Omqondofana	(1S)-1,2,3,4-Tetrahydronaphthalene-1-Carboxylic acid
Inombolo ye-CAS	85977-52-2
Inombolo yeCAT	I-RF-CC111
Isimo Sesitoko	Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani
I-Molecular Formula	I-C11H12O2
Isisindo samangqamuzana	176.21
Ukuminyana	1.186g/cm3
I-Melting Point	54.0 ~ 56.0℃
Iphuzu elibilayo	342.7°C ku-760 mmHg
I-Refractive Index	1.576
Ibhrendi	I-Ruifu Chemical

Imininingwane:

Into	Imininingwane
Ukubukeka	I-Crystalline Powder Emhlophe noma Cishe Emhlophe
I-Chemical Purity	≥99.0%
Enantimoer Excess	ee ≥99.0%
Ukungcola Kwe-Isomer	≤1.0%
Ukulahlekelwa Ekumisweni	≤0.50%
Hlobisa Into	≤1.0%
Umswakama (KF)	≤1.0%
Ukuzungezisa Okuqondile [α]_D²⁰	-59.0°~ -63.0°(C=0.3 ku-Benzence)
Izinsimbi Ezisindayo	≤20ppm
Isitoreji	5-8℃ Ukungangeni moya
Izinga Lokuhlola	I-Enterprise Standard
Ukusetshenziswa	I-Palonosetron Hydrochloride (CAS: 135729-62-3) Abaphakathi

(S)-1,2,3,4-tetrahydro-1-Naphthoic Acid CAS: 85977-52-2 Route of Synthesis

Iphakheji nesitoreji:

Iphakheji: Ibhodlela, I-Cardboard Drum, 25kg/Drum, noma ngokwezidingo zekhasimende.

Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni, umswakama kanye nezinambuzane.

Izinzuzo:

I-FAQ:

Isicelo:

I-Shanghai Ruifu Chemical Co., Ltd. ingumkhiqizi ohamba phambili kanye nomphakeli we-(S)-1,2,3,4-Tetrahydro-1-Naphthoic Acid (CAS: 85977-52-2) enekhwalithi ephezulu.Kuyinto ephakathi ngokuvamile ekuhlanganiseni kwePalonosetron Hydrochloride (CAS: 135729-62-3).

I-Palonosetron Hydrochloride (i-CAS: 135729-62-3) iyinoveli engu-5-HT3 receptor antagonist eyethulwe njenge-ejenti ejovayo yokuvimbela isicanucanu esinamandla nokubambezeleka kanye nokuhlanza okuhambisana ne-chemotherapy yomdlavuza.Inengxenye yempilo ende kakhulu (~40 h) kunabanye abaphikisi be-5-HT3 abatholakala njengamanje, enikeza izinzuzo ezisebenzayo ekuvimbeleni ukubambezeleka kwesicanucanu nokuhlanza okwenzeka ngemva kwamahora angu-24 futhi kufika ezinsukwini eziyisithupha ngemva kokuphathwa ngamakhemikhali.Nge-1,2,3,4-tetrahydro-1-Naphthoic Acid njengento yokuqala, ukuhlukaniswa, ukukhishwa, ukunciphisa, i-cyclization, usawoti we-palonosetron hydrochloride granisetron.