(S)-1,2,3,4-Tetrahydro-1-Naphthoic Acid CAS 85977-52-2 Purity ≥99.0% ee≥99.0% I-Palonosetron Hydrochloride Intermediate Factory
I-Commercial Supply Palonosetron Hydrochloride kanye Nezixhumanisi Ezihlobene:
(S)-1,2,3,4-Tetrahydro-1-Naphthoic Acid CAS: 85977-52-2
(R)-1,2,3,4-Tetrahedro-1-Naphthoic Acid CAS: 23357-47-3
(S)-3-Aminoquinuclidine Dihydrochloride CAS: 119904-90-4
I-3-Quinuclidinone Hydrochloride CAS: 1193-65-3
I-1-Naphthoic Acid CAS: 86-55-5
I-Palonosetron Hydrochloride CAS: 135729-62-3 API
Igama Lekhemikhali | (S)-1,2,3,4-Tetrahydro-1-Naphthoic Acid |
Omqondofana | (1S)-1,2,3,4-Tetrahydronaphthalene-1-Carboxylic acid |
Inombolo ye-CAS | 85977-52-2 |
Inombolo yeCAT | I-RF-CC111 |
Isimo Sesitoko | Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani |
I-Molecular Formula | I-C11H12O2 |
Isisindo samangqamuzana | 176.21 |
Ukuminyana | 1.186g/cm3 |
I-Melting Point | 54.0 ~ 56.0℃ |
Iphuzu elibilayo | 342.7°C ku-760 mmHg |
I-Refractive Index | 1.576 |
Ibhrendi | I-Ruifu Chemical |
Into | Imininingwane |
Ukubukeka | I-Crystalline Powder Emhlophe noma Cishe Emhlophe |
I-Chemical Purity | ≥99.0% |
Enantimoer Excess | ee ≥99.0% |
Ukungcola Kwe-Isomer | ≤1.0% |
Ukulahlekelwa Ekumisweni | ≤0.50% |
Hlobisa Into | ≤1.0% |
Umswakama (KF) | ≤1.0% |
Ukuzungezisa Okuqondile [α]D20 | -59.0°~ -63.0°(C=0.3 ku-Benzence) |
Izinsimbi Ezisindayo | ≤20ppm |
Isitoreji | 5-8℃ Ukungangeni moya |
Izinga Lokuhlola | I-Enterprise Standard |
Ukusetshenziswa | I-Palonosetron Hydrochloride (CAS: 135729-62-3) Abaphakathi |
(S)-1,2,3,4-tetrahydro-1-Naphthoic Acid CAS: 85977-52-2 Route of Synthesis
Iphakheji: Ibhodlela, I-Cardboard Drum, 25kg/Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni, umswakama kanye nezinambuzane.
![1](https://a395.goodao.net/uploads/15.jpg)
![2](https://a395.goodao.net/uploads/23.jpg)
I-Shanghai Ruifu Chemical Co., Ltd. ingumkhiqizi ohamba phambili kanye nomphakeli we-(S)-1,2,3,4-Tetrahydro-1-Naphthoic Acid (CAS: 85977-52-2) enekhwalithi ephezulu.Kuyinto ephakathi ngokuvamile ekuhlanganiseni kwePalonosetron Hydrochloride (CAS: 135729-62-3).
I-Palonosetron Hydrochloride (i-CAS: 135729-62-3) iyinoveli engu-5-HT3 receptor antagonist eyethulwe njenge-ejenti ejovayo yokuvimbela isicanucanu esinamandla nokubambezeleka kanye nokuhlanza okuhambisana ne-chemotherapy yomdlavuza.Inengxenye yempilo ende kakhulu (~40 h) kunabanye abaphikisi be-5-HT3 abatholakala njengamanje, enikeza izinzuzo ezisebenzayo ekuvimbeleni ukubambezeleka kwesicanucanu nokuhlanza okwenzeka ngemva kwamahora angu-24 futhi kufika ezinsukwini eziyisithupha ngemva kokuphathwa ngamakhemikhali.Nge-1,2,3,4-tetrahydro-1-Naphthoic Acid njengento yokuqala, ukuhlukaniswa, ukukhishwa, ukunciphisa, i-cyclization, usawoti we-palonosetron hydrochloride granisetron.
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