(S)-3-Hydroxypyrrolidine Hydrochloride CAS 122536-94-1 Purity ≥98.0% (GC) I-Darifenacin Hydrobromide Intermediate
Umkhiqizi onobumsulwa obuphezulu kanye nenani elincintisanayo
Ukunikezwa Kwezohwebo Okuhlobene Ne-Darifenacin Hydrobromide:
(S)-3-Hydroxypyrrolidine Hydrochloride CAS: 122536-94-1
(S)-α,α-Diphenyl-3-Pyrrolidineacetamide L-Tartrate CAS: 134002-26-9
(S)-2,2-Diphenyl-2-(Pyrrolidin-3-yl)acetonitrile Hydrobromide CAS: 194602-27-2
(S)-2,2-Diphenyl-2-(1-Tosylpyrrolidin-3-yl)acetonitrile CAS: 133099-09-9
2,3-Dihydrobenzofuran CAS: 496-16-2
I-2,3-Dihydrobenzofuranyl-5-Acetic Acid CAS: 69999-16-2
I-5-(2-Bromoethyl)-2,3-Dihydrobenzofuran CAS: 127264-14-6
I-Darifenacin Hydrobromide CAS: 133099-07-7
| Igama Lekhemikhali | (S) -3-Hydroxypyrrolidine Hydrochloride |
| Omqondofana | (S)-3-Hydroxypyrrolidine HCl;(S)-3-Pyrrolidinol Hydrochloride;(S)-Pyrrolidin-3-ol (Hydrochloride);(S)-Pyrrolidin-3-ol, i-HCl |
| Inombolo ye-CAS | 122536-94-1 |
| Inombolo yeCAT | I-RF-CC103 |
| Isimo Sesitoko | Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani |
| I-Molecular Formula | I-C4H10ClNO |
| Isisindo samangqamuzana | 123.581 |
| I-Melting Point | 104°C kuya ku-107°C |
| Iphuzu elibilayo | 108°C ukuya ku-110°C (8mmHg) |
| Ukuncibilika | I-DMSO (Kancane), i-Methanol (Kancane) |
| Isimo Sokuthumela | Kuthunyelwe Ngaphansi Kwezinga Lokushisa Le-Ambient |
| Ibhrendi | I-Ruifu Chemical |
| Into | Imininingwane |
| Ukubukeka | I-Off-White ukuya ku-Brown Crystalline Powder |
| I-Chemical Purity | ≥98.0% (GC) |
| Ukuzungezisa okuqondile | +6.5° ~ +8.5° (C=3 CH3OH) |
| Noma yikuphi Ukungcola Komuntu Ngamunye | ≤0.50% |
| Ukungcola Okuphelele | ≤2.0% |
| Ukulahlekelwa Ekumisweni | ≤0.50% |
| Izinsalela ekushiseni | ≤0.50% |
| Izinga Lokuhlola | I-Enterprise Standard |
| Ukusetshenziswa | I-Darifenacin Hydrobromide (CAS: 133099-07-7) Okumaphakathi |
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I-Shanghai Ruifu Chemical Co., Ltd. ingumkhiqizi oholayo nomphakeli we-(S)-3-Hydroxypyrrolidine Hydrochloride (CAS: 122536-94-1) enekhwalithi ephezulu, esetshenziswa kabanzi ku-organic synthesis, ukuhlanganiswa kwemithi ephakathi kwemithi kanye nesithako Semithi Esisebenzayo (API) synthesis.(S)-3-Hydroxypyrrolidine Hydrochloride (CAS: 122536-94-1) iyinhloko emaphakathi ye-Darifenacin Hydrobromide (CAS: 133099-07-7).
I-Darifenacin Hydrobromide (i-CAS: i-133099-07-7), i-oral esebenzayo, i-M3 receptor antagonist ekhethiwe kanye ngosuku, yasungulwa ukuze zelashwe esinyeni esisebenza ngokweqile ezigulini ezinezimpawu zokuphuthuma komchamo, ukuphuthuma kanye nemvamisa.Umuthi uvimbela ngokukhethekile i-M3 receptor ku-muscle detrusor ngenkathi usindisa i-M1 ne-M2 receptors okukholelwa ukuthi ihileleke ohlelweni lwezinzwa oluphakathi nokusebenza kwenhliziyo ngokulandelana.Ikhompiyutha ekuqaleni yasungulwa ngabakwaPfizer futhi yanikezwa ilayisense kwaNovartis naseBayer.
