I-Sevelamer Carbonate CAS 845273-93-0 API Factory High Purity
Ukunikezela Komkhiqizi Ngokuhlanzeka Okuphezulu kanye Nekhwalithi Ezinzile
Igama Lekhemikhali: Sevelamer Carbonate
I-CAS: 845273-93-0
I-Sevelamer Carbonate iyi-amine ye-polymeric ebopha i-phosphate futhi isetshenziselwa ukwelapha i-hyperphosphatemia ezigulini ezinesifo sezinso esingamahlalakhona.
Ikhwalithi ephezulu ye-API, Ukukhiqiza Kwezentengiso
Igama Lekhemikhali | Sevelamer carbonate |
Omqondofana | I-2-Propen-1-Amine Polymer ene-(Chloromethyl)Oxirane Carbonate |
Inombolo ye-CAS | 845273-93-0 |
Inombolo yeCAT | I-RF-API28 |
Isimo Sesitoko | Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani |
I-Molecular Formula | (C3H7N)m.(C3H5ClO)n.(CH2O3)x |
Isisindo samangqamuzana | 211.64 |
Ibhrendi | I-Ruifu Chemical |
Into | Imininingwane |
Ukubukeka | Impushana Emhlophe ukuya Kophuzi |
Ukuhlonza A | Nge-IR, Ukufanisa nezinga lokusebenza |
Ukuhlonza B | Kufanele kube ukusabela okuhle |
I-Chloride | ≤0.10% |
Ukulahlekelwa Ekumisweni | ≤10.0% |
Izinsalela ekushiseni | ≤0.20% |
Izinsimbi Ezisindayo | ≤20ppm |
Ukuhlolwa kokuncibilika | Kufanele ihambisane nesilinganiso |
Ukubopha kwePhosphate | 3.0~7.0mmol/g |
I-Oligomer encibilikayo | ≤0.20% |
Izinga Lokuhlola | I-Enterprise Standard |
Ukunaka | Vikela ekukhanyeni futhi Gcina endaweni epholile eyomile(≤5℃), Ukusetshenziswa okungcono kakhulu phakathi kwezinyanga eziyisithupha |
Ukusetshenziswa | I-Active Pharmaceutical Ingredient (API) |
Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, isigubhu seCardboard, 25kg/Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni, umswakama kanye nezinambuzane.
I-Sevelamer carbonate iyi-amine ye-polymeric ebopha i-phosphate futhi isetshenziselwa ukwelapha i-HYPERPHOSPHATEMIA ezigulini ezinesifo sezinso.I-Sevelamer carbonate i-anion exchange resin, enesakhiwo se-polymeric esifanayo ne-sevelamer hydrochloride, lapho i-carbonate ithatha indawo ye-chloride njenge-counterion.Ngenkathi ama-counterions ehluka kusawoti amabili, i-polymer ngokwayo, i-moiety esebenzayo ehilelekile ekubopheni i-phosphate, iyafana.I-Sevelamer carbonate yaziwa ngamakhemikhali ngokuthi i-poly(allylamine-co-N,N'-diallyl-1,3diamino-2-hydroxypropane) usawoti we-carbonate.I-Sevelamer carbonate i-hygroscopic, kodwa ayincibiliki emanzini.I-Sevelamer Carbonate, i-polymer engamuncwe iyinhlanganisela ye-phosphate yomlomo ezigulini ezinenkinga yezinso.Kubikwa ukuthi i-Sevelamer Carbonate mancane amathuba okuba ibangele i-hypercalcemia, amazinga aphansi e-PTH, nokubala okuqhubekayo kwe-coronary and aortic calcification ezigulini ze-hemodialysis kune-calcium-based phosphate binder.