I-Sitagliptin Triazole Hydrochloride CAS 762240-92-6 Purity >99.0% (HPLC) Isithombe Esifakiwe Sefekthri Sekhwalithi Ephezulu

I-Sitagliptin Triazole Hydrochloride CAS 762240-92-6 Purity >99.0% (HPLC) Factory High Quality

Incazelo emfushane:

Igama: I-Sitagliptin Triazole Hydrochloride

I-CAS: 762240-92-6

Ubumsulwa: >99.0% (HPLC)

Ukubukeka: I-Crystalline Powder Emhlophe ukuya Kokumhlophe

I-Sitagliptin Phosphate Monohydrate emaphakathi (CAS: 654671-77-9) yokwelashwa kwesifo sikashukela sohlobo II

Ikhwalithi Ephezulu, Ukukhiqizwa Kwezohwebo

E-Mail: alvin@ruifuchem.com

Thumela i-imeyili kithi

Imininingwane Yomkhiqizo

Imikhiqizo Ehlobene

Omaka bomkhiqizo

Incazelo:

Thola Izimo Ezihlobene Ne-Sitagliptin Phosphate Monohydrate:
I-Sitagliptin API CAS 486460-32-6
I-Sitagliptin Phosphate Monohydrate API CAS 654671-77-9
2,4,5-Trifluorophenylacetic Acid CAS 209995-38-0
I-Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acid CAS 486460-00-8
I-Sitagliptin Triazole Hydrochloride CAS 762240-92-6
I-Sitagliptin Phosphate Monohydrate Intermediate CAS 486460-21-3

Chemical Properties:

Igama Lekhemikhali	3-(Trifluoromethyl) -5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine Hydrochloride
Omqondofana	I-Sitagliptin Triazole Hydrochloride;I-Sitagliptin Intermediate A
Inombolo ye-CAS	762240-92-6
Inombolo yeCAT	I-RF-PI1193
Isimo Sesitoko	Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani
I-Molecular Formula	C6H7F3N4·HCl
Isisindo samangqamuzana	228.60
I-Melting Point	236.0~246.0℃
Ukuncibilika	I-Soluble ku-Methanol
Ibhrendi	I-Ruifu Chemical

Imininingwane:

Into	Imininingwane
Ukubukeka	I-Crystalline Powder emhlophe ukuya kokumhlophe
Ukuhlonza nge-HPLC	Isikhathi sokugcinwa kwesampula sihambisana nezinga lokubhekisela
Ukuhlonzwa nge-IR	Iyahambisana
Ukulahlekelwa Ekumisweni	<0.50%
Izinto Ezihlobene
Noma Ikuphi Ukungcola Okukodwa	<0.50%
Ukungcola Okuphelele	<1.00%
Izinsimbi Ezisindayo	<20ppm
Ukuhlanzeka / Indlela Yokuhlaziya	>99.0% (HPLC)
Izinga Lokuhlola	I-Enterprise Standard
Ukusetshenziswa	Okumaphakathi kwe-Sitagliptin Phosphate Monohydrate (CAS: 654671-77-9)

Iphakheji nesitoreji:

Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwezidingo zekhasimende.

Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni nakumswakama.

Izinzuzo:

I-FAQ:

Isicelo:

I-3-(Trifluoromethyl)-5,6,7,8-tetrahydro--[1,2,4]triazolo[4,3-a]pyrazine Hydrochloride (CAS: 762240-92-6) iphakathi kwe-Sitagliptin Phosphate Monohydrate ( I-CAS: 654671-77-9), okuyi-oral-bioavailable selective inhibitor ye-DPP4 etholwe ngokulungiselelwa kwekilasi lama-inhibitor e-DPP4 asuselwa ku-β-aminoacid.Yehlisa umsebenzi we-DPP4 ngendlela eqhubekayo kulandela ukuphathwa kanye ngosuku, igcina amazinga ajikelezayo e-GIP engaguquki kanye ne-GLP1 ngemuva kokudla kuzo zombili izifundo ezibucayi nezingamahlalakhona futhi yehlisa amazinga kashukela egazini ngaphandle kokwenyuka okukhulu kwe-hypoglycemia.I-Sitagliptin Phosphate (STG) isetshenziselwa ukwelapha uhlobo 2 lwe-DM ngoba ithuthukisa ukulawulwa kwe-glycemic ngokwandisa amazinga ama-incretin hormone asebenzayo, i-GLP-1 (peptide-1) ne-GIP (i-insulinotropic peptide encike kuglucose).I-STG yavunywa yi-FDA ngo-2006.