I-Sitagliptin Triazole Hydrochloride CAS 762240-92-6 Purity >99.0% (HPLC) Factory High Quality
Thola Izimo Ezihlobene Ne-Sitagliptin Phosphate Monohydrate:
I-Sitagliptin API CAS 486460-32-6
I-Sitagliptin Phosphate Monohydrate API CAS 654671-77-9
2,4,5-Trifluorophenylacetic Acid CAS 209995-38-0
I-Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acid CAS 486460-00-8
I-Sitagliptin Triazole Hydrochloride CAS 762240-92-6
I-Sitagliptin Phosphate Monohydrate Intermediate CAS 486460-21-3
Igama Lekhemikhali | 3-(Trifluoromethyl) -5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine Hydrochloride |
Omqondofana | I-Sitagliptin Triazole Hydrochloride;I-Sitagliptin Intermediate A |
Inombolo ye-CAS | 762240-92-6 |
Inombolo yeCAT | I-RF-PI1193 |
Isimo Sesitoko | Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani |
I-Molecular Formula | C6H7F3N4·HCl |
Isisindo samangqamuzana | 228.60 |
I-Melting Point | 236.0~246.0℃ |
Ukuncibilika | I-Soluble ku-Methanol |
Ibhrendi | I-Ruifu Chemical |
Into | Imininingwane |
Ukubukeka | I-Crystalline Powder emhlophe ukuya kokumhlophe |
Ukuhlonza nge-HPLC | Isikhathi sokugcinwa kwesampula sihambisana nezinga lokubhekisela |
Ukuhlonzwa nge-IR | Iyahambisana |
Ukulahlekelwa Ekumisweni | <0.50% |
Izinto Ezihlobene | |
Noma Ikuphi Ukungcola Okukodwa | <0.50% |
Ukungcola Okuphelele | <1.00% |
Izinsimbi Ezisindayo | <20ppm |
Ukuhlanzeka / Indlela Yokuhlaziya | >99.0% (HPLC) |
Izinga Lokuhlola | I-Enterprise Standard |
Ukusetshenziswa | Okumaphakathi kwe-Sitagliptin Phosphate Monohydrate (CAS: 654671-77-9) |
Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni nakumswakama.
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I-3-(Trifluoromethyl)-5,6,7,8-tetrahydro--[1,2,4]triazolo[4,3-a]pyrazine Hydrochloride (CAS: 762240-92-6) iphakathi kwe-Sitagliptin Phosphate Monohydrate ( I-CAS: 654671-77-9), okuyi-oral-bioavailable selective inhibitor ye-DPP4 etholwe ngokulungiselelwa kwekilasi lama-inhibitor e-DPP4 asuselwa ku-β-aminoacid.Yehlisa umsebenzi we-DPP4 ngendlela eqhubekayo kulandela ukuphathwa kanye ngosuku, igcina amazinga ajikelezayo e-GIP engaguquki kanye ne-GLP1 ngemuva kokudla kuzo zombili izifundo ezibucayi nezingamahlalakhona futhi yehlisa amazinga kashukela egazini ngaphandle kokwenyuka okukhulu kwe-hypoglycemia.I-Sitagliptin Phosphate (STG) isetshenziselwa ukwelapha uhlobo 2 lwe-DM ngoba ithuthukisa ukulawulwa kwe-glycemic ngokwandisa amazinga ama-incretin hormone asebenzayo, i-GLP-1 (peptide-1) ne-GIP (i-insulinotropic peptide encike kuglucose).I-STG yavunywa yi-FDA ngo-2006.
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I-Sitagliptin CAS 486460-32-6 Ubumsulwa >99.0% (HPLC...
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I-Sitagliptin Phosphate Monohydrate CAS 654671-77...
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2,4,5-Trifluorophenylacetic Acid CAS 209995-38-...
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I-Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Buty...
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I-Sitagliptin Triazole Hydrochloride CAS 762240-9...
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I-Sitagliptin Phosphate Monohydrate Intermediate ...