I-Sodium 4-Aminosalicylate CAS 133-10-8 Ubumsulwa >99.0% (HPLC)

Incazelo emfushane:

Igama Lekhemikhali: I-Sodium 4-Aminosalicylate

CAS: 133-10-8

Ubumsulwa: >99.0% (HPLC)

Ukubukeka: I-Crystalline Powder Emhlophe noma Engamhlophe

Ikhwalithi Ephezulu, Ukukhiqizwa Kwezohwebo

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Imininingwane Yomkhiqizo

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Incazelo:

I-Shanghai Ruifu Chemical Co., Ltd. ingumkhiqizi oholayo kanye nomphakeli we-Sodium 4-Aminosalicylate (CAS: 133-10-8) enekhwalithi ephezulu.Singahlinzeka nge-COA, ukulethwa komhlaba wonke, amanani amancane kanye nenqwaba etholakalayo.Uma unentshisekelo kulo mkhiqizo, sicela uthumele imininingwane enemininingwane ehlanganisa inombolo ye-CAS, igama lomkhiqizo, nenani kithi.Please contact: alvin@ruifuchem.com

Chemical Properties:

Igama Lekhemikhali I-sodium 4-aminosalicylate
Omqondofana I-4-Amino-Salicylic Acid Sodium Salt;4-Amino-2-Hydroxybenzoic Acid Sodium Salt;4-Aminosalicylic Acid Sodium Salt;i-sodium p-aminosalicylate;p-Aminosalicylic Acid Sodium Salt
Inombolo ye-CAS 133-10-8
Inombolo yeCAT RF2771
Isimo Sesitoko Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani
I-Molecular Formula I-C7H6NNaO3
Isisindo samangqamuzana 175.12
I-Melting Point 265.0~270.0℃
Kuyazwela I-Hygroscopic
Ukuncibilika Incibilika Kalula Emanzini, Incibilika Kancane ku-Ethanol, Ayincibiliki ku-acetone
Ibhrendi I-Ruifu Chemical

Imininingwane:

Into Imininingwane
Ukubukeka I-Crystalline Powder Emhlophe noma Engamhlophe
Ukuhlanzeka / Indlela Yokuhlaziya >99.0% (HPLC)
Amanzi (nguKarl Fischer) <2.00%
3-Aminophenol <0.25%
Ukungcola Okuphelele <1.00%
I-Infrared Spectrum Ivumelana Nesakhiwo
I-Proton NMR Spectrum Ivumelana Nesakhiwo
Izinga Lokuhlola I-Enterprise Standard
Ukusetshenziswa Abalamuli Bezemithi;I-Agent ye-Antitubercular

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Isicelo:

I-sodium 4-Aminosalicylate (CAS: 133-10-8) incibilika kalula emanzini, incibilika kancane ku-ethanol, ayincibiliki ku-acetone.Ingasetshenziswa njengemithi elwa nesifo sofuba, ikakhulukazi ekwelapheni okuphelele kokutheleleka ngesifo sofuba.Lo mkhiqizo ufana ne-4-Aminobenzoic acid (PABA) ngesakhiwo, i-congener ye-PABA.Ivimbela ukukhula nokukhiqizwa kabusha kwe-Mycobacterium tuberculosis ngokuvimbela ukuncintisana kwe-folate synthesis.Lo mkhiqizo usebenza kuphela ngokumelene ne-mycobacteria, hhayi i-mycobacteria ye-atypical.Uma isetshenziswa iyodwa, ingakhula ngokushesha ukumelana nomuthi.Lo mkhiqizo kufanele uhlanganiswe neminye imishanguzo elwa nesifo sofuba, njenge-streptomycin ne-isoniazid, engabambezela ukukhiqizwa kokumelana nomuthi we-bacilli yesifo sofuba kuze kube yileyo emibili yokugcina.Ngokomtholampilo, isetshenziselwa ikakhulukazi isifo sofuba samaphaphu nesangaphandle kwamaphaphu esibangelwa i-Mycobacterium tuberculosis.Ibuye isetshenziswe ku-hyperthyroidism futhi inomthelela onamandla ekwehliseni i-lipids yegazi.Ifakwe kahle epheshaneni le-GI.Imuncwa ngokushesha kunamanye ama-salicylic acid.Ngemva kokumuncwa, isatshalaliswa ngokushesha oketshezini oluhlukahlukene lomzimba futhi ifinyelela ekugxiliseni okuphezulu kakhulu oketshezini lwe-pleural, kodwa ukugxila kuketshezi lwe-cerebrospinal kuphansi kakhulu.Umkhiqizo usakazeka ngokushesha ezicutshini zezinso, zamaphaphu nesibindi, ufinyelele ukugxila okuphezulu ezicutshini ze-caseous.Ilungele isifo sofuba se-pulmonary kanye ne-extrapulmonary esibangelwa isifo sofuba i-Mycobacterium.I-sodium para-aminosalicylate iphumelela kuphela ngokumelene ne-mycobacteria hhayi ngokumelene ne-mycobacteria engekho.Ukungazweli kungakhula ngokushesha uma isetshenziswa iyodwa, ngakho-ke kufanele ihlanganiswe neminye imishanguzo yokulwa ne-TB.I-Streptomycin ne-isoniazid, lapho zihlanganiswa nazo, zingabambezela ukukhula kokumelana nomuthi we-Mycobacterium tuberculosis emithini yomibili.Isetshenziswa kakhulu njengomuthi wokulwa nesifo sofuba womugqa wesibili.Ingase futhi isetshenziselwe i-hyperthyroidism, futhi ifaneleka kakhulu ezigulini ezine-hyperthyroidism nesifo sofuba.Uma i-iodine ejenti ingasebenzi futhi iphazamisa ukusebenza, ingathathwa isikhathi esifushane ukudala izimo zokusebenza.Ukujova ngomjovo ngokuvamile kusetshenziswa ezimweni ezimbi kakhulu njenge-tuberculous meningitis.

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