I-Sodium Valproate (VPA) CAS 1069-66-5 API Factory High Purity
Umkhiqizi Wezentengiso Ngokuhlanzeka Okuphezulu kanye Nekhwalithi Ezinzile
Igama Lekhemikhali: I-Sodium Valproate (VPA)
I-CAS: 1069-66-5
Igama Lekhemikhali | I-Sodium Valproate |
Omqondofana | I-VPA;I-Valproic Acid Sodium Salt;I-Sodium 2-Propylpentanoate |
Inombolo ye-CAS | 1069-66-5 |
Inombolo yeCAT | I-RF-API14 |
Isimo Sesitoko | Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani |
I-Molecular Formula | I-C8H15NaO2 |
Isisindo samangqamuzana | 166.20 |
I-Melting Point | 300 ℃ |
Ukuminyana | 1.0803 g/cm3 |
Ukuncibilika kwamanzi | Incibilika Emanzini |
Isimo Sokuthumela | Ngaphansi Kwezinga Lokushisa Le-Ambient |
Ibhrendi | I-Ruifu Chemical |
Into | Imininingwane |
Ukubukeka | I-Crystalline Powder Emhlophe noma Cishe Emhlophe, I-Hygroscopic |
Ukuhlonza | I-Infrared Spectrum Ngokuqhathanisa kwe-RT Ukusabela kweSodium Salt |
Ukuncibilika | Incibilika Kakhulu Emanzini, Incibilika Ngokukhululekile ku-Ethanol |
I-acidity noma i-alkalinity | Ngokusho kwe-EP Criterions |
Ukucaca Nombala Wesixazululo | Ngokusho kwe-EP Criterions |
Izinsimbi Ezisindayo | ≤20ppm |
Ama-sulfate | ≤200ppm |
I-Chloride | ≤200ppm |
Ukulahlekelwa Ekumisweni | ≤2.0% |
Noma yikuphi Ukungcola | ≤0.10% (GC) |
Ukungcola Okuphelele | ≤0.30% (GC) |
Isivivinyo | 98.5%~101.0% (Titration) |
Izinga Lokuhlola | I-European Pharmacopeia (EP) |
Ukusetshenziswa | I-Active Pharmaceutical Ingredient (API) |
Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, isigubhu seCardboard, 25kg/Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni, umswakama kanye nezinambuzane.
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I-Sodium Valproate (CAS: 1069-66-5) i-anticonvulsant futhi i-ejenti ephumelelayo yokulawula kokubili ukungabikho kanye nokubanjwa ngokuyinhloko okujwayelekile kwe-tonic-clonic.I-Valproic acid sodium salt (Sodium Valproate) iyi-histone deacetylase (HDAC) inhibitor, ene-IC50 ebangeni le-0.5 ne-2 mM, futhi ivimbela i-HDAC1 (IC50, 400 μM), futhi idala ukuwohloka kwe-proteasomal ye-HDAC2.I-Valproic acid usawoti we-sodium yenza kusebenze ukusayinda kwe-Notch1 futhi ivimbele ukwanda kumaseli amancane omdlavuza wamaphaphu (SCLC).I-Sodium Valproate (i-CAS: i-1069-66-5) isetshenziselwa ukwelapha isithuthwane, i-bipolar disorder kanye nokuvimbela ikhanda le-migraine.
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