I-Sofosbuvir CAS 1190307-88-0 Ubumsulwa ≥99.0% (HPLC)
| Igama | I-Sofosbuvir |
| Omqondofana | GS-7977;I-PSI-7977 |
| Inombolo ye-CAS | 1190307-88-0 |
| Isimo Sesitoko | Esitokweni, Isikali Sokukhiqiza Sifika Emakhulwini Amakhilogremu |
| I-Molecular Formula | I-C22H29FN3O9P |
| Isisindo samangqamuzana | 529.45 |
| I-Melting Point | 120.0~125.0℃ |
| Ukuminyana | 1.41 |
| Ukuncibilika | I-Soluble ku-DMF, DMSO, Ethanol |
| Isimo Sokuthumela | Ngaphansi Kwezinga Lokushisa Le-Ambient |
| I-COA ne-MSDS | Iyatholakala |
| Umsuka | Shanghai, China |
| I-Shelf Life | Izinyanga Ezingama-36 Uma Zigcinwe Ngokufanelekile |
| Ibhrendi | I-Ruifu Chemical |
| Into | Imininingwane |
| Ukubukeka | I-Crystalline Powder emhlophe ukuya kokumhlophe |
| Ukuhlonza | I-HPLC;I-RT |
| Ukuhlanzeka / Indlela Yokuhlaziya | ≥99.0% (HPLC) |
| EE | ≥99.0% |
| Ukulahlekelwa Ekumisweni | ≤1.0% |
| Izinsalela ekushiseni | ≤0.20% |
| Ukungcola Okukodwa | ≤0.50% |
| Ukungcola Okuphelele | ≤1.0% |
| Izinsimbi Ezisindayo | ≤20ppm |
| Izincibilikisi Ezisele | Hlangana nezidingo zokucaciswa |
| I-Methanol | ≤1500ppm |
| I-TBME | ≤2500ppm |
| I-Dichloromethane | ≤720ppm |
| I-Tetrahydrofuran | ≤720ppm |
| I-Toluene | ≤60ppm |
| Izinga Lokuhlola | I-Enterprise Standard |
| Ukusetshenziswa | I-Sofosbuvir (CAS: 1190307-88-0) ekwelapheni i-Hepatitis C Virus (HCV) |
Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, 25kg/Drum, noma ngokwezidingo zekhasimende
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni, umswakama
I-Sofosbuvir (CAS: 1190307-88-0) (ebhalwe ngokusemthethweni njenge-PSI-797, GS-7977) iyi-phosphoramidate prodrug kanye ne-nucleotide polymerase inhibitor yokwelapha ukutheleleka kwegciwane le-hepatitis C (HCV) elingamahlalakhona.Kunconywa ukuthi kusetshenziswe ngokuhambisana nezinye izidakamizwa (njenge-velpatasvir) ekwelashweni komugqa wokuqala kwe-HCV genotypes 1, 2, 3, 4, 5, kanye no-6. Kusebenza ngokusebenza njenge-nucleotide analog inhibitor, ekwazi ukuvimbela ngokukhethekile i-HCV NS5B (i-non-structural protein 5B) i-RNA polymerase encike ku-RNA.
