I-Taurine CAS 107-35-7 Assay 99.0~101.0% Ikhwalithi ephezulu Yefektri

I-Taurine (CAS: 107-35-7) Indlela Yokuhlola ye-JP
I-Taurine, uma yomisiwe, iqukethe okungaphansi kuka-99.0% futhi hhayi ngaphezu kwe-101.0% ye-C2H7NO3S.
I-Taurine yenzeka njengamakristalu angenambala noma amhlophe, noma impushana ecwebezelayo emhlophe.
Iyancibilika emanzini, futhi ayincibiliki ku-ethanol (99.5).
I-pH yesisombululo esilungiswe ngokuncibilikisa i-1.0 g ye-Taurine ku-20 mL wamanzi asanda kubiliswa napholile iphakathi kuka-4.1 no-5.6.
Ukuhlonza Thola i-spectrum yokumuncwa kwe-infrared ye-Taurine njengoba kuqondiswe endleleni yediski ye-potassium bromide ngaphansi kwe-Infrared Spectrophotometry <2.25>, futhi uqhathanise i-spectrum ne-Reference Spectrum: yomibili i-spectra ibonisa ukuqina okufanayo kokumuncwa ezinombolweni zamagagasi afanayo.
Ukuhlanzeka (1) Ukucaca kanye nombala wesixazululo-Isixazululo esitholakala ngokuncibilikisa i-1.0 g ye-Taurine ku-20 mL wamanzi icacile futhi ayinambala.
(2) I-Chloride <1.03>-Yenza ukuhlolwa nge-1.0 g ye-Taurine.Lungiselela ikhambi lokulawula ngo-0.30 mL we-0.01mol/L hydrochloric acid VS (hhayi ngaphezu kuka-0.011%).
(3) I-sulfate <1.14>-Yenza ukuhlolwa nge-2.0 g ye-Taurine.Lungiselela ikhambi lokulawula ngo-0.40 mL we-0.005 mol/L sulfuric acid VS (hhayi ngaphezu kuka-0.010%).
(4) I-Ammonium <1.02>-Yenza ukuhlolwa nge-0.25 g ye-Taurine.Lungiselela ikhambi lokulawula ngo-5.0 mL we-Standard Ammonium Solution (hhayi ngaphezu kuka-0.02%).
(5) Izinsimbi ezinzima <1.07>-Qhubeka ne-2.0 g ye-Taurine ngokweNdlela 1, futhi wenze ukuhlolwa.Lungiselela isixazululo sokulawula ngo-2.0 mL we-Standard lead Solution (hhayi ngaphezu kuka-10 ppm).
(6) I-Iron <1.10>-Lungisa isisombululo sokuhlola nge-2.0 g ye-Taurine ngokweNdlela 1, futhi wenze ukuhlolwa ngokweNdlela A. Lungiselela isisombululo sokulawula nge-2.0 mL ye-Standard Iron Solution (hhayi ngaphezu kwe-10 ppm).
(7) Izinto ezihlobene-Chaza u-1.0 g we-Taurine ku-50 mL wamanzi, futhi usebenzise lesi sixazululo njengesixazululo esiyisampula.Ipayipi elingu-1 mL lesixazululo sesampula, bese wengeza amanzi ukwenza u-50 mL ncamashi.Ipayipi elingu-1 mL lalesi sixazululo, engeza amanzi ukwenza u-10 mL ngqo, bese usebenzisa lesi sixazululo njengesixazululo esijwayelekile.Yenza ukuhlolwa ngalezi zixazululo njengoba kuqondiswe ngaphansi kwe-Thin-layer Chromatography <2.03>.Faka i-5mL ngayinye yesixazululo sesampula kanye nesisombululo esijwayelekile epuletini lejeli ye-silica yechromatography yongqimba oluncane.Yakha ipuleti ngengxube yamanzi, i-ethanol (99.5), i-1-butanol ne-acetic acid (100) (150:150:100:1) ibe yibanga elingaba ngu-10 cm, futhi womise ipuleti ngomoya.Fafaza ngokulinganayo i-ninhydrin-butanol TS epuletini, futhi ushise ku-105 ℃ imizuzu emi-5: indawo ngaphandle kwendawo eyisimiso enesixazululo sesampula ayikho ngaphezu kwendawo eyodwa, futhi ayishubi ngaphezu kwendawo enesixazululo esivamile. .
Ukulahlekelwa ekumisweni <2.41> Hhayi ngaphezulu kuka-0.20% (1 g, 105℃, amahora angu-2).
Insalela ekuthungeleni <2.44>Ayidluli ku-0.1% (1 g).
I-Assay Kala ngokunembile cishe u-0.2 g we-Taurine, omisiwe ngaphambilini, ncibilika ku-50 mL wamanzi, engeza u-5 mL wesisombululo se-formaldehyde, kanye ne-titrate<2.50>no-0.1 mol/L i-sodium hydroxide VS (i-potentiometric titration).Yenza isinqumo esingenalutho ngendlela efanayo, futhi wenze noma yikuphi ukulungisa okudingekayo.
I-mL ngayinye ka-0.1 mol/L i-sodium hydroxide VS ＝12.52 mg ye-C2H7NO3S
Iziqukathi nokugcinaIziqukathi-Iziqukathi ezivalwe kahle.

I-Taurine (CAS: 107-35-7) Indlela Yokuhlola ye-USP
INCAZELO
I-Taurine iqukethe i-NLT 98.5% kanye ne-NMT 101.5% ye-taurine (C2H7NO3S), ebalwa ngokomiswa.
UKUKHOMBA
• A. UKUMUMVA OKUNOMTHWALO <197K>
ISIVIVINYO
• UKUNIKEZWA KWENITROGEN, Indlela II <461>
Ukuhlaziya: Qhubeka njengoba uqondiswe esahlukweni.I-mL ngayinye ka-0.01 N sulfuric acid ilingana no-1.25 mg we-C2H7NO3S.
Indlela yokwamukela: 98.5% -101.5% ngesisekelo esomisiwe
UKUNGCOLA
• OKUSELELE EKUSHISENI <281>: NMT 0.3%
• I-CHLORIDE NE-SULFATE, I-Chloride <221>
Okujwayelekile: 0.50 mL ka-0.020 N hydrochloric acid
Isampula: 0.7 g weTaurine
Indlela yokwamukela: NMT 0.05%
• I-CHLORIDE NE-SULFATE, i-Sulfate <221>
Okujwayelekile: 0.25 mL ka-0.020 N sulfuric acid
Isampula: 0.8 g ye-Taurine
Indlela yokwamukela: NMT 0.03%
• IRON <241>: NMT 30 ppm
• IZIMTHETHO EZISINDAYO, Indlela I <231>: NMT 15 ppm
• AMACOMPOUND ESIPHATHELENE
Isixazululo esijwayelekile: 0.05 mg/mL ye-USP Taurine RS emanzini ukuhlangana okulingana okungaba ngu-0.5% wesisombululo Sesampuli
Isixazululo sesampula: 10 mg/mL ye-Taurine emanzini
Isistimu yeChromatographic
(Bona i-Chromatography <621>, I-Thin-Layer Chromatography.)
Imodi: TLC
I-Adsorbent: 0.25-mm ungqimba lwengxube yejeli yesilica yechromatographic
Ivolumu yohlelo lokusebenza: 5 µL
Ukuthuthukisa uhlelo lokuncibilikisa: I-Butyl alcohol, i-glacial acetic acid, namanzi (3:1:1)
I-reagent yokufutha: 2 mg/mL we-ninhydrin engxubeni ye-butyl alcohol kanye no-2 N acetic acid (95:5)
Ukuhlaziya: Sula ipuleti ku-80 ° imizuzu engama-30.Fafaza ipuleti nge-spray reagent, bese ushisa ku-80 ° cishe imizuzu eyi-10.Hlola ipuleti ngaphansi kokukhanya okumhlophe.[QAPHELA-Inani le-RF lezindawo ze-taurine kufanele libe ngu-0.2.]
Imibandela yokwamukela: Ayikho indawo yesibili yesisombululo Sesampuli enkulu noma eqine kakhulu kunendawo eyinhloko yesixazululo Esijwayelekile.
Ukungcola komuntu ngamunye: NMT 0.5%
IZIVIVINYO EZITHILE
• UKULAHLEKELWA EKOMISENI <731>: Yomisa isampula ku-105° amahora angu-3: ilahlekelwa yi-NMT ngo-0.3% wesisindo sayo.
IZIDINGO EZENGEZIWE
• UKUPAKASHA KANYE NESIGCINI: Londoloza ezitsheni ezivalwe kahle.
• AMAZINGA EREferensi e-USP <11>
I-USP Taurine RS