I-Tenofovir CAS 147127-20-6 Assay 98.0%~102.0% API Anti-HIV Factory
I-Tenofovir Commercial Related Intermediate:
I-Tenofovir CAS: 147127-20-6
I-Tenofovir Disoproxil Fumarate CAS 202138-50-9
I-Tenofovir Alafenamide Hemifumarate CAS 1392275-56-7
I-Chloromethyl Isopropyl Carbonate CAS 35180-01-9
I-Diethyl (p-Toluenesulfonyloxymethyl)phosphonate CAS 31618-90-3
(R)-(+)-Propylene Carbonate CAS 16606-55-6
(R)-9-(2-Hydroxypropyl)adenine CAS 14047-28-0
I-Diethyl (Hydroxymethyl)phosphonate CAS 3084-40-0
I-Adenine CAS 73-24-5
Igama | I-Tenofovir |
Omqondofana | (R)-PMPA;(R)-9-(2-Phosphonomethoxypropyl)I-Adenine |
Inombolo ye-CAS | 147127-20-6 |
Inombolo yeCAT | I-RF-API07 |
Isimo Sesitoko | Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani |
I-Molecular Formula | I-C9H14N5O4P |
Isisindo samangqamuzana | 287.22 |
I-Melting Point | 276.0-280.0℃ |
Ibhrendi | I-Ruifu Chemical |
Into | Imininingwane |
Ukubukeka | I-Crystalline Powder Emhlophe noma Cishe Emhlophe |
Indlela Yokuhlola / Yokuhlaziya | 98.0%~102.0% (kwisisekelo se-anhydrous) |
Ukuncibilika | Incibilika Kancane Emanzini (0.1g ku-100ml);Ayincibiliki ku-Methanol(0.01g ku-100ml nangaphezulu) |
Ukuhlonza UV | I-Absorbance cishe ku-261nm |
Ukuhlonza HPLC | Isikhathi sokugcinwa kwenani eliphakeme eliyinhloko kusampula yokuhlola kufanele sihambisane naleso sezinga |
I-Sulfate Ash | ≤1.5% |
Amanzi (KF) | ≤3.0% |
I-Specific Optical Rotation | -19.0° ~ -23.0° (ku-25℃ isisekelo se-anhydrous) |
I-PMPA Monoester Ukungcola | ≤1.5% (HPLC) |
Noma yikuphi Ukungcola Okukodwa Okukhulu | ≤0.5% (HPLC) |
Ukungcola Okuphelele | ≤3.0% (HPLC) |
I-Enantiomeric Purity | ≤0.5% (HPLC) |
9-Propenyl Adenine | ≤75ppm (HPLC) |
Izinga Lokuhlola | I-Enterprise Standard |
Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni, umswakama.
I-Tenofovir (CAS: 147127-20-6) iyi-analogue ye-acyclic phosphonate nucleotide kanye ne-reverse-transcriptase inhibitor (NtRTI).Isetshenziswa njenge-ejenti elwa ne-HIV.I-Antiviral.I-Tenofovir disoproxil (Viread) iyi-analogue yokuqala ye-nucleotide egunyazwe yi-FDA yaseMelika ukwelapha izifo ze-HIV-1.I-Tenofovir umuthi osetshenziselwa ukwelapha i-heptatitis B engapheli kanye nokuvimbela nokwelashwa kwe-HIV/AIDS.Ivimbela umsebenzi we-HIV reverse transcriptase ngokuncintisana ne-substrate yemvelo i-deoxyadenosine 5'-triphosphate, okubangela ukuqedwa kochungechunge lwe-DNA.