I-Tenofovir Disoproxil Fumarate CAS 202138-50-9 Assay 98.0%~102.0% Isithombe Esifakiwe Sefektri ye-API

I-Tenofovir Disoproxil Fumarate CAS 202138-50-9 Assay 98.0%~102.0% API Factory

Incazelo emfushane:

Igama Lekhemikhali: I-Tenofovir Disoproxil Fumarate

I-CAS: 202138-50-9

Ukubukeka: Impushana Emhlophe noma Cishe Emhlophe

I-Assay: 98.0%~102.0% (ngokwesisekelo esingenamanzi)

I-nucleotide reverse transcriptase inhibitor esetshenziselwa ukwelapha i-HIV kanye ne-Chronic Hepatitis B.

Ikhwalithi Ephezulu, Ukukhiqizwa Kwezohwebo

E-Mail: alvin@ruifuchem.com

Thumela i-imeyili kithi

Imininingwane Yomkhiqizo

Imikhiqizo Ehlobene

Omaka bomkhiqizo

Incazelo:

I-Tenofovir Commercial Related Intermediate:
I-Tenofovir CAS: 147127-20-6
I-Tenofovir Disoproxil Fumarate CAS 202138-50-9
I-Tenofovir Alafenamide Hemifumarate CAS 1392275-56-7
I-Chloromethyl Isopropyl Carbonate CAS 35180-01-9
I-Diethyl (p-Toluenesulfonyloxymethyl)phosphonate CAS 31618-90-3
(R)-(+)-Propylene Carbonate CAS 16606-55-6
(R)-9-(2-Hydroxypropyl)adenine CAS 14047-28-0
I-Diethyl (Hydroxymethyl)phosphonate CAS 3084-40-0
I-Adenine CAS 73-24-5

Chemical Properties:

Igama Lekhemikhali	I-Tenofovir Disoproxil Fumarate
Omqondofana	I-Tenofovir DF;I-Bis(POC)-PMPA Fumarate;GS 4331 Fumarate
Inombolo ye-CAS	202138-50-9
Inombolo yeCAT	I-RF-API106
Isimo Sesitoko	Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani
I-Molecular Formula	I-C23H34N5O14P
Isisindo samangqamuzana	635.52
I-Melting Point	113.0 ukuze 115.0 ℃
Ibhrendi	I-Ruifu Chemical

Imininingwane:

Into	Imininingwane
Ukubukeka	Impushana Emhlophe noma Ecishe Emhlophe
Ukuhlonza A	I-IR Spectrum Ihambisana Nezinga Lereferensi
Ukuhlonza B	Isikhathi sokugcina sesiqongo esikhulu esivela kusixazululo sesampula sihambisana naleso sesixazululo esijwayelekile, njengoba sitholwe ekuhlolweni.
Isivivinyo	98.0%~102.0% (kwisisekelo se-anhydrous)
Amanzi	≤1.0%
I-Fumaric Acid	17.5%~19.0%
Izinsalela ekushiseni	≤0.20%
Izinsimbi Ezisindayo	≤20ppm
I-Chloromethyl isopropyl carbonate	≤0.15%
Izinto Ezihlobene
I-Tenofovir	≤0.15%
I-Adenine	≤0.15%
I-Tenofovir Isoproxi Monoester	≤1.0%
I-Tenofovir Disoproxil Ethyl Ester	≤0.15%
I-Tenofovir Isopropyl Isoproxil	≤0.30%
I-Tenofovir Disoproxil Carbamate	≤0.15%
I-Tenofovir Disproxil	≤0.15%
Noma Ikuphi Ukungcola Okukodwa	≤0.10%
Ukungcola Okuphelele	≤2.0%
Izinga Lokuhlola	I-Enterprise Standard
Ukusetshenziswa	I-API

Iphakheji nesitoreji:

Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwezidingo zekhasimende.

Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni nakumswakama.

Izinzuzo:

I-FAQ:

Isicelo:

I-Tenofovir Disoproxil Fumarate (CAS: 202138-50-9), i-prodrug ye-tenofovir (Igama lokuhweba: Viread) ethuthukiswe i-Gilead Sciences, iwuhlobo lwezidakamizwa ze-nucleotide-analogues ze-antiretroviral, eziqala ukusebenza ngokusebenza njenge-reverse transcriptase inhibitors[nRTIs] , evimba i-reverse transcriptase, i-enzyme ebalulekile ekukhiqizeni amagciwane kubantu abane-HIV.Kufanele kuqashelwe ukuthi iyi-nucleotide reverse transcriptase inhibitor yokuqala eyake yasetshenziswa ekwelapheni ukutheleleka nge-HIV.I-Tenofovir Disoproxil Fumarate iguqulelwa ku-tenofovir in vivo, okuyi-acyclic nucleoside phosphonate[nucleotide] analog ye-adenosine 5'-monophosphate.Ngokuvamile isetshenziswa ngokuhlanganiswa nezinye izinhlobo zemithi.Imithi ye-HIV ayikwazi ukwelapha i-HIV/AIDS, kodwa ukuphuza inhlanganisela yemithi ye-HIV [okuthiwa uhlelo lwe-HIV] nsuku zonke kungasiza abantu abane-HIV baphile isikhathi eside, izimpilo ezinempilo.Ngokusekelwe kumbhalo we-FDA, i-tenofovir disoproxil fumarate ingaba futhi eyokwelapha ukutheleleka kwegciwane le-hepatitis B [HBV] elingamahlalakhona kubantu abadala nasezinganeni ezineminyaka engu-12 nangaphezulu.