tert-Butyl 4-(6-Nitropyridin-3-yl)piperazine-1-Carboxylate CAS 571189-16-7 Purity >98.0% (HPLC) Palbociclib Intermediate Factory

Incazelo emfushane:

Igama Lekhemikhali: tert-Butyl 4-(6-Nitropyridin-3-yl)piperazine-1-Carboxylate

Amazwi afanayo: 1-Boc-4-(6-Nitro-3-Pyridyl)piperazine

I-CAS: 571189-16-7

Ubumsulwa: >98.0% (HPLC)

Ukubukeka: Okunsundu Okukhanyayo kuya Kuphuphu Olunsundu

I-Intermediate of Palbociclib (CAS: 571190-30-2)

E-Mail: alvin@ruifuchem.com

Thumela i-imeyili kithi

Imininingwane Yomkhiqizo

Imikhiqizo Ehlobene

Omaka bomkhiqizo

Incazelo:

I-Ruifu Chemical Supply Palbociclib Related Intermediate:
I-Palbociclib CAS 571190-30-2
5-Bromo-2,4-Dichloropyrimidine CAS 36082-50-5
5-Bromo-2-Chloro-N-Cyclopentylpyrimidin-4-Amine CAS 733039-20-8
tert-Butyl 4-(6-Nitropyridin-3-yl)piperazine-1-Carboxylate CAS 571189-16-7
tert-Butyl 4-(6-Amino-3-Pyridyl)piperazine-1-Carboxylate CAS 571188-59-5
6-Bromo-2-Chloro-8-Cyclopentyl-5-Methylpyrido-[2,3-d]pyrimidin-7(8H)-one CAS 1016636-76-2
2-Chloro-8-Cyclopentyl-5-Methyl-8H-Pyrido[2,3-d]pyrimidin-7-one CAS 1013916-37-4

Chemical Properties:

Igama Lekhemikhali	I-tert-Butyl 4-(6-Nitropyridin-3-yl)piperazine-1-Carboxylate
Omqondofana	I-1-Boc-4-(6-Nitro-3-Pyridyl)piperazine;4-(6-Nitro-3-pyridinyl)-1-Piperazinecarboxylic Acid tert-Butyl Ester;i-tert-Butyl 4-(6-Nitro-3-Pyridinyl)-1-Piperazinecarboxylate
Inombolo ye-CAS	571189-16-7
Inombolo yeCAT	I-RF-PI1850
Isimo Sesitoko	Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani
I-Molecular Formula	I-C14H20N4O4
Isisindo samangqamuzana	308.33
Ibhrendi	I-Ruifu Chemical

Imininingwane:

Into	Imininingwane
Ukubukeka	Impushana Ensundu Ekhanyayo ukuya Ensundu
Ukuhlanzeka / Indlela Yokuhlaziya	>98.0% (HPLC)
I-LCMS	Ihambisana Nesakhiwo
Ukulahlekelwa Ekumisweni	<1.00%
Ukungcola Okuphelele	<2.00%
Izinga Lokuhlola	I-Enterprise Standard
Ukusetshenziswa	I-Intermediate of Palbociclib (CAS: 571190-30-2)

Iphakheji nesitoreji:

Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwemfuneko yekhasimende

Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni nakumswakama

Izinzuzo:

I-FAQ:

Isicelo:

I-tert-Butyl 4-(6-nitropyridin-3-yl)piperazine-1-carboxylate (CAS: 571189-16-7) iyindawo emaphakathi ye-Palbociclib (CAS: 571190-30-2).I-Palbociclib (eyaziwa nangokuthi inombolo ehlanganisiwe PD-0332991) isidakamizwa esihlolwayo sokwelapha umdlavuza webele esakhiwa yi-Pfizer.Kuyi-inhibitor ekhethiwe ye-cyclin-dependent kinases CDK4 ne-CDK6.I-Palbociclib ivimba ukuqhubeka komjikelezo weseli ukusuka kusigaba G1 ukuya ku-S ngokuvimbela i-CDK4/6-dependent retinoblastoma (RB) phosphorylation.I-Palbociclibhas isetshenziselwe ukwelapha i-HER2 negative, i-estrogen receptor (ER) umdlavuza webele we-metastatic we-metastatic.