I-Tolvaptan CAS 150683-30-0 API Purity >99.0% (HPLC)
I-Tolvaptan Yomkhiqizi kanye Nezixhumanisi Ezihlobene:
I-Tolvaptan CAS 150683-30-0
7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-one CAS 160129-45-3
o-Toluoyl Chloride CAS 933-88-0
I-4-Amino-2-Methylbenzoic Acid CAS 2486-75-1
I-2-Methyl-4-Nitrobenzoic Acid CAS 1975-51-5
| Igama | I-Tolvaptan |
| Igama Lekhemikhali | N- [4-(9-chloro-6-hydroxy-2-azabicyclo[5.4.0]undeca-8,10,12-triene-2-carbonyl)-3-methyl-phenyl]-2-methyl-benzamide |
| Inombolo ye-CAS | 150683-30-0 |
| Inombolo yeCAT | I-RF-API101 |
| Isimo Sesitoko | Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani |
| I-Molecular Formula | I-C26H25ClN2O3 |
| Isisindo samangqamuzana | 448.94 |
| Ibhrendi | I-Ruifu Chemical |
| Into | Imininingwane |
| Ukubukeka | I-Crystalline Powder emhlophe ukuya kokumhlophe |
| Izindlela Zokuhlonza | IR, HPLC |
| Ukuncibilika | Incibilika ku-Benzyl Alcohol ne-Methanol kodwa Ayincibiliki Emanzini ne-Hexane |
| Ukuhlanzeka / Indlela Yokuhlaziya | >99.0% (HPLC) |
| I-Melting Point | 219.0~222.0℃ |
| Ukulahlekelwa Ekumisweni | <0.50% |
| Izinsalela ekushiseni | <0.10% |
| Ukungcola Okukodwa | <0.50% |
| Ukungcola Okuphelele | <1.00% |
| Izinsimbi Ezisindayo | ≤20ppm |
| Izincibilikisi Ezisele | Hlangana nencazelo |
| Izinga Lokuhlola | I-Enterprise Standard |
| Ukusetshenziswa | I-API;Pharmaceutical Intermediates |
Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwemfuneko yekhasimende
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni nakumswakama
I-Tolvaptan (CAS: 150683-30-0), eyaziwa nangokuthi i-OPC-41061, iyisitha esikhethiwe, esincintisana ne-arginine vasopressin receptor 2 esetshenziselwa ukwelapha i-hyponatremia (amazinga aphansi e-sodium yegazi) ahlotshaniswa nokuhluleka kwenhliziyo, i-cirrhosis, kanye nesifo se-syndrome. i-hormone ye-antidiuretic engalungile (SIADH).I-Otsuka Pharmaceutical enelayisensi ye-tolvaptan ngaphansi kwegama lokuhweba i-Samsca ngemuva kokuthi i-FDA igunyaze umuthi ngoMeyi 2009. I-Tolvaptan iphinde yabonisa ukusebenza ngempumelelo ekulweni nesifo sezinso se-polycystic.Ocwaningweni lwango-2004, i-tolvaptan esetshenziswa nge-diuretics yendabuko yaphawuleka ukuthi inyusa ukuphuma koketshezi oluningi futhi ithuthukise amazinga e-sodium egazini ezigulini ezinokwehluleka kwenhliziyo ngaphandle kokukhiqiza imiphumela emibi efana ne-hypotension (umfutho wegazi ophansi) noma i-hypokalemia (ukwehla kwamazinga e-potassium egazi).Umuthi futhi awuzange ubonise umthelela omubi ekusebenzeni kwezinso.
![7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-one CAS 160129-45-3 Tolvaptan Intermediate](https://www.ruifuchemical.com/uploads/7-Chloro-1234-tetrahydrobenzobazepin-5-one-CAS-160129-45-3-300x300.jpg)
