I-Valdecoxib CAS 181695-72-7 Ubumsulwa >99.5% (HPLC)

Incazelo emfushane:

Igama Lekhemikhali: Valdecoxib

I-CAS: 181695-72-7

Ubumsulwa: >99.5% (HPLC)

Ukubukeka: Impushana Emhlophe noma Engamhlophe

I-API, I-Second-Generation COX-2 Inhibitor

Thintana: UDkt. Alvin Huang

Iselula/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


Imininingwane Yomkhiqizo

Imikhiqizo Ehlobene

Omaka bomkhiqizo

Incazelo:

I-Shanghai Ruifu Chemical Co., Ltd. ingumkhiqizi oholayo kanye nomphakeli we-Valdecoxib (CAS: 181695-72-7) enekhwalithi ephezulu.Singahlinzeka nge-COA, ukulethwa komhlaba wonke, amanani amancane kanye nenqwaba etholakalayo.Uma unentshisekelo kulo mkhiqizo, sicela uthumele imininingwane enemininingwane ehlanganisa inombolo ye-CAS, igama lomkhiqizo, nenani kithi.Please contact: alvin@ruifuchem.com

Chemical Properties:

Igama Lekhemikhali I-Valdecoxib
Omqondofana I-Bextra;SC 65872;I-Valus;Valz;4-(5-Methyl-3-Phenyl-4-Isooxazolyl)benzenesulfonamide;4-(5-Methyl-3-Phenyl-1,2-Oxazol-4-yl)benzenesulfonamide;4-(5-Methyl-3-Phenylisoxazol-4-yl)benzenesulfonamide
Inombolo ye-CAS 181695-72-7
Inombolo yeCAT I-RF2833
Isimo Sesitoko Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani
I-Molecular Formula I-C16H14N2O3S
Isisindo samangqamuzana 314.36
I-Melting Point 162.0~167.0℃
Iphuzu elibilayo 481.2±55.0℃
Ukuminyana 1.303±0.06 g/cm3
Kuyazwela Ukushisa Kuyazwela
Ukuncibilika kwamanzi Ayincibiliki Emanzini
Ukuncibilika I-Soluble ku-Ethanol, i-Methanol
Isikhathi Sokugcina. Ukushisa Kwegumbi
Ibhrendi I-Ruifu Chemical

Imininingwane:

Into Imininingwane
Ukubukeka Impushana Emhlophe noma Engamhlophe
Ukuhlanzeka / Indlela Yokuhlaziya >99.5% (HPLC)
I-Melting Point 162.0~167.0℃
Amanzi (nguKarl Fischer) <0.50%
Izinsalela ekushiseni <0.20%
Ukungcola Okukodwa <0.30%
Ukungcola Okuphelele <0.50%
Izinsimbi Ezisindayo (njenge-Pb) <20ppm
I-Infrared Spectrum Ivumelana Nesakhiwo
I-NMR Spectrum Ivumelana Nesakhiwo
Izinga Lokuhlola I-Enterprise Standard
Ukusetshenziswa I-API, I-Second-Generation COX-2 Inhibitor

Iphakheji nesitoreji:

Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwemfuneko yekhasimende

Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni nakumswakama

Izinzuzo:

Amandla Anele: Izinsiza ezanele kanye nochwepheshe

Isevisi Yobuchwepheshe: Isevisi yokuthenga yokuma eyodwa

Iphakheji le-OEM: Iphakheji yangokwezifiso kanye nelebula iyatholakala

Ukulethwa Okusheshayo: Uma kungaphakathi kwesitoko, ukulethwa kwezinsuku ezintathu kuqinisekisiwe

Impahla Ezinzile: Gcina isitoko esinengqondo

Ukusekelwa Kwezobuchwepheshe: Isixazululo sezobuchwepheshe siyatholakala

Isevisi Yokuhlanganisa Ngokwezifiso: Isukela kumagremu kuye kumakhilo

Ikhwalithi Ephezulu: Kusungulwe uhlelo oluphelele lokuqinisekisa ikhwalithi

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IkhwalithiIsiqiniseko?Isistimu yokulawula ikhwalithi eqinile.Imishini yobuchwepheshe yokuhlaziya ifaka i-NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, NOMA, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, njll.

Amasampula?Imikhiqizo eminingi inikeza amasampula wamahhala wokuhlolwa kwekhwalithi, izindleko zokuthumela kufanele zikhokhelwe amakhasimende.

Ukuhlolwa Kwemboni?Wamukelekile ekucwaningweni kwemboni.Sicela wenze i-aphoyintimenti kusengaphambili.

I-MOQ?Ayikho i-MOQ.I-oda elincane liyamukeleka.

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Isicelo:

I-Valdecoxib (i-CAS: 181695-72-7) iyi-inhibitor yesizukulwane sesibili i-COX-2, eyakhiwe njengokulandelela ku-celecoxib yokwelashwa ngomlomo kanye ngosuku kwe-osteoarthritis, i-arthritis ye-rheumatoid yabantu abadala kanye nobuhlungu bokuya esikhathini.I-Valdecoxib icishe ikhethe izikhathi ezingama-28,000 uma iqhathaniswa ne-COX-2 eyenziwe kabusha yomuntu kune-COX-1 eyenziwe kabusha.Ku-ex viva human assay yegazi lonke, amanani e-I&O ngokumelene ne-COX-2 ne-COX-1 ngokulandelana ayengu-0.89 PM kanye no-25.4 FM.Kumamodeli ezilwane, i-valdecoxib inomsebenzi womlomo omuhle kakhulu njenge-anti-inflammatory.Kumagundane, i-valdecoxib ivimbele ngokunamandla i-carrageenan footpad edema kanye nesifo samathambo esidalwa yi-adjuvant.I-Valdecoxib iyisidakamizwa esingezona ukuvuvukala (i-NSAID) esibonisa izakhiwo zokulwa nokuvuvukala, ezidambisa ubuhlungu kanye ne-antipyretic kumamodeli ezilwane.Kuyi-inhibitor enamandla futhi ekhethiwe ye-prostaglandin synthesis ngokuyinhloko ngokuvinjelwa kwe-COX-2.I-Valdecoxib isetshenziselwa ukukhulula ezinye izimpawu ezibangelwa isifo sokuqaqamba kwamalunga (rheumatism), njengokuvuvukala, ukuvuvukala, ukuqina, nobuhlungu bamalunga.I-Valdecoxib igunyazelwe ukukhululeka kwezimpawu nezimpawu ze-osteoarthritis kanye nesifo samathambo sabadala kanye nokwelashwa kwe-dysmenorrhea eyinhloko.I-Valdecoxib ivinjelwa ekwelapheni ubuhlungu bangemva kokuhlinzwa ngokushesha ngemva kokuhlinzwa kwe-graft ye-coronary artery bypass.

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