I-Zoledronic Acid Monohydrate CAS 165800-06-6 Purity ≥99.0% API Factory High Purity
Umkhiqizi onokuhlanzeka Okuphezulu kanye Nekhwalithi Ezinzile
Igama Lekhemikhali: Zoledronic Acid Monohydrate
I-CAS: 165800-06-6
I-bisphosphonate enamandla kakhulu ne-activator ye-PKC
Ikhwalithi ephezulu ye-API, Ukukhiqiza Kwezentengiso
Igama Lekhemikhali | I-Zoledronic Acid Monohydrate |
Inombolo ye-CAS | 165800-06-6 |
Inombolo yeCAT | I-RF-API56 |
Isimo Sesitoko | Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani |
I-Molecular Formula | I-C5H12N2O8P2 |
Isisindo samangqamuzana | 290.1 |
Ibhrendi | I-Ruifu Chemical |
Into | Imininingwane |
Ukubukeka | Impushana Emhlophe noma Cishe Ikristalu |
Ukuhlonza | I-IR Spectrum;I-HPLC ChromatogramI-UV-Vis: Kukhona ukumunca okuphezulu ku-210nm |
pH | 2.0~4.0 |
Ukuncibilika | Incibilika kancane kusixazululo esingu-0.1N sodium hydroxide, inyibilika kancane emanzini kanye ne-0.1N hydrochloric acid, cishe engancibiliki ku-ethanol. |
Ukucaca Nombala | Isixazululo kufanele sicace futhi singabi mbala;uma i-opalescent, akufanele idlule i-opalescent kunokumiswa kwereferensi 1;uma inemibala, ingabi nombala ogqamile kuno-Y2 |
Ukungcola Okukodwa | ≤0.50% |
Ukungcola Okuphelele | ≤1.0% |
Ukulahlekelwa Ekumisweni | 5.0%~8.0% |
I-Chloride | ≤0.02% |
I-Phosphate | ≤0.50% |
I-Phosphite | ≤0.50% |
Izinsimbi Ezisindayo | ≤10ppm |
Ubumsulwa | ≥99.0% |
Izinga Lokuhlola | I-Enterprise Standard |
Ukusetshenziswa | I-API |
Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, isigubhu seCardboard, 25kg/Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni, umswakama kanye nezinambuzane.
I-Zoledronic acid monohydrate iyi-bisphosphonate enamandla kakhulu kanye ne-activator ye-PKC.Zoledronic acid monohydrate iyi-heterocyclic bisphosphonate ebhekwa njengamandla aphezulu kakhulu e-bisphosphonates yokucindezela ukukhuphuka kwamathambo futhi iye yasetshenziswa ezifundweni eziningana ze-osteoporosis.I-Zoledronic acid monohydrate iyi-inhibitor ye-ASM ne-FDPS kanye ne-activator ye-PKC.I-Zoledronic acid (i-zoledronate) iyi-bisphosphonate bone resorption inhibitor, inhibitor ye-farnesyl diphosphate (FPP) synthase eholela ekuvimbeleni okuphansi komsebenzi we-osteoclast nokunciphisa ukubuyiswa kwamathambo kanye nokuguqulwa.Isetshenziselwe ukwelapha i-postmenopausal osteoporosis, isifo sikaPaget, i-hypercalcemia, kanye ne-chemotherapy yomdlavuza ukwelapha ukulimala kwamathambo okubangelwa umdlavuza osusabalele emathanjeni.